UK Age-Related Macular Degeneration Therapeutics Market Analysis

UK Age-Related Macular Degeneration Therapeutics Market Analysis


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The UK Age-Related Macular Degeneration (AMD) Therapeutics Market was valued at US $281 Mn in 2022 and is predicted to grow at a CAGR of 6.90% from 2023 to 2030, to US $479 Mn by 2030. The key drivers of this industry include the upward trend in the prevalence of age-related macular degeneration, advancements in treatment, and other factors. Major players in the industry include Regeneron Pharmaceuticals, Novartis, Bayer, Roche, Genentech, and other notable companies.

ID: IN10GBPH427 CATEGORY: Pharmaceuticals GEOGRAPHY: UK AUTHOR: Riddhi Solanki

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UK Age-Related Macular Degeneration Therapeutics Market Analysis: Executive Summary

The UK Age-Related Macular Degeneration (AMD) Therapeutics Market is at around US $281 Mn in 2022 and is projected to reach US $479 Mn in 2030, exhibiting a CAGR of 6.90% during the forecast period.

Age-related macular degeneration (AMD) is a progressive eye condition that primarily affects older individuals, potentially resulting in significant vision loss. It specifically targets the macula, responsible for central vision, which can make tasks such as reading challenging. The condition is associated with risk factors such as diabetes, smoking, and other lifestyle factors. AMD manifests in two primary forms: dry AMD and wet AMD. Symptoms include distorted vision, difficulty seeing clearly, and a gradual decline in eyesight. Treatment options comprise anti-VEGF therapy, utilizing medications like Lucentis, Vabysmo, Avastin (developed by Genentech), and Eylea (produced by Regeneron Pharmaceuticals). Additionally, preventive measures encompass laser therapy and the intake of nutritional supplements like zinc and copper.

It is estimated that the prevalence of AMD is around 17% in the age group of 65 years and older in the UK, where approximately 663 new cases per million per year of AMD occur. Thus, the prevalence is directly proportional to age. The market is primarily influenced by key factors such as the growth of the aging population and the consequent rise in prevalence, advancements in treatment, and increased government initiatives expanding the therapeutics industry. However, shortage of human resources and the high cost of treatments like gene therapy and laser surgery, which are implemented in response to demand, limit the market's potential.

UK Age-Related Macular Degeneration Therapeutics Market Analysis 2022 to 2030

Market Dynamics

Market Growth Drivers

Increased aging population: The estimated proportion of the elderly population aged 65 and above in the UK is about 17%. The reported prevalence of AMD is around 2.9% in the age group of 65–69 years, approximately 15% between 85 and 90 years, and more than 21% for people above 90 years of age. The UK witnesses about 663 new cases of AMD per million per year, accounting to around 39,800 people. These estimates suggest a growing demographic shift in the UK, resulting in a larger pool of patients and increased market demand.

Advancements in treatment: The UK government is fostering numerous collaborations and research initiatives between pharmaceutical companies and academic institutions, promoting clinical trials and projects such as the London Project to Cure Blindness. Continuous research introduces innovative medications such as Vuity and delivery systems like nanotechnology featuring extended dosing intervals. This broadens the range of treatment choices, accommodating individual patient preferences and demand in the market.

Supportive government initiatives: The UK National Health Service (NHS) is currently providing universal healthcare coverage that provides anti-VEGF medications for most citizens. The NHS also aims to include advanced therapies such as gene therapy in its coverage to increase outreach and market penetration.

Market Restraints

Limited accessibility: Disparities in access to specialists and healthcare facilities beyond major cities are evident, particularly in scarcely populated areas. Limited availability of specialized ophthalmologists, optometrists, and advanced care options contributes to geographical inequalities in healthcare, leading to delayed diagnoses that restrict market growth.

Economic constraints: The conventional method for managing wet AMD, which includes administering anti-VEGF injections, comes with a substantial cost and requires frequent treatments. The price per dose of Lucentis solution is expensive, posing a significant financial burden on both the NHS and individual patients, consequently limiting market penetration. Although the NHS provides coverage for essential medical care, their high-cost novel therapies, such as gene therapy, prove be challenging to afford for the population

Notable Updates

May 2022, The National Institute for Health and Care Excellence (NICE) released preliminary guidelines for the NHS, suggesting the use of Roche's Faricimab as a treatment for both wet age-related macular degeneration (AMD) and diabetic macular oedema (DMO).

Healthcare Policies and Regulatory Landscape

The healthcare policy and regulatory framework in the United Kingdom are governed by various significant authorities and agencies. Key entities responsible for healthcare regulations and licensing in the UK include the Medicines and Healthcare Products Regulatory Agency (MHRA) and the Care Quality Commission (CQC). The MHRA oversees the regulation of medicines, medical devices, and related services, while the CQC is responsible for ensuring the quality and safety of care provided by healthcare providers in England.

Obtaining a license for healthcare products in the UK necessitates compliance with the regulations set forth by these authorities. Companies seeking registration and marketing authorization for pharmaceuticals and medical devices must receive approval from the MHRA. This entails submitting technical and scientific data to validate the product's safety, quality, and effectiveness.

The healthcare policy and regulatory framework in the United Kingdom involve a multitude of authorities and agencies, with the MHRA and CQC playing pivotal roles in overseeing healthcare product regulations. Opportunities for companies in the healthcare industry are diverse in both the public and private healthcare sectors in the country.

Competitive Landscape

Key Players

  • F. Hoffman-La-Roche Ltd
  • Regeneron Pharmaceuticals
  • Novartis AG
  • Apellis Pharmaceuticals
  • Neurotech Pharmaceuticals
  • Bayer
  • Pfizer Inc
  • Genetech
  • Kanghong Pharma
  • Bausch Health Companies, Inc

1. Executive Summary
1.1 Disease Overview
1.2 Global Scenario
1.3 Country Overview
1.4 Healthcare Scenario in Country
1.5 Patient Journey
1.6 Health Insurance Coverage in Country
1.7 Active Pharmaceutical Ingredient (API)
1.8 Recent Developments in the Country

2. Market Size and Forecasting
2.1 Epidemiology of Disease
2.2 Market Size (With Excel & Methodology)
2.3 Market Segmentation (Check all Segments in Segmentation Section)

3. Market Dynamics
3.1 Market Drivers
3.2 Market Restraints

4. Competitive Landscape
4.1 Major Market Share

4.2 Key Company Profile (Check all Companies in the Summary Section)

4.2.1 Company
4.2.1.1 Overview
4.2.1.2 Product Applications and Services
4.2.1.3 Recent Developments
4.2.1.4 Partnerships Ecosystem
4.2.1.5 Financials (Based on Availability)

5. Reimbursement Scenario
5.1 Reimbursement Regulation
5.2 Reimbursement Process for Diagnosis
5.3 Reimbursement Process for Treatment

6. Methodology and Scope

UK Age-Related Macular Degeneration Therapeutics Market Segmentation

By Disease Type

  • Dry AMD
  • Wet AMD

By Drug

  • Lucentis
  • Eylea
  • Beovu

By Age Group

  • Less than 60
  • Between 60-80
  • More than 80

By Stage

  • Early AMD
  • Intermediate AMD
  • Advanced AMD
  • No AMD

By Distribution Channel

  • Hospital Pharmacy
  • Specialty Pharmacy
  • Online Pharmacy

Methodology for Database Creation

Our database offers a comprehensive list of healthcare centers, meticulously curated to provide detailed information on a wide range of specialties and services. It includes top-tier hospitals, clinics, and diagnostic facilities across 30 countries and 24 specialties, ensuring users can find the healthcare services they need.​

Additionally, we provide a comprehensive list of Key Opinion Leaders (KOLs) based on your requirements. Our curated list captures various crucial aspects of the KOLs, offering more than just general information. Whether you're looking to boost brand awareness, drive engagement, or launch a new product, our extensive list of KOLs ensures you have the right experts by your side. Covering 30 countries and 36 specialties, our database guarantees access to the best KOLs in the healthcare industry, supporting strategic decisions and enhancing your initiatives.

How Do We Get It?

Our database is created and maintained through a combination of secondary and primary research methodologies.

1. Secondary Research

With many years of experience in the healthcare field, we have our own rich proprietary data from various past projects. This historical data serves as the foundation for our database. Our continuous process of gathering data involves:

  • Analyzing historical proprietary data collected from multiple projects.
  • Regularly updating our existing data sets with new findings and trends.
  • Ensuring data consistency and accuracy through rigorous validation processes.

With extensive experience in the field, we have developed a proprietary GenAI-based technology that is uniquely tailored to our organization. This advanced technology enables us to scan a wide array of relevant information sources across the internet. Our data-gathering process includes:

  • Searching through academic conferences, published research, citations, and social media platforms
  • Collecting and compiling diverse data to build a comprehensive and detailed database
  • Continuously updating our database with new information to ensure its relevance and accuracy

2. Primary Research

To complement and validate our secondary data, we engage in primary research through local tie-ups and partnerships. This process involves:

  • Collaborating with local healthcare providers, hospitals, and clinics to gather real-time data.
  • Conducting surveys, interviews, and field studies to collect fresh data directly from the source.
  • Continuously refreshing our database to ensure that the information remains current and reliable.
  • Validating secondary data through cross-referencing with primary data to ensure accuracy and relevance.

Combining Secondary and Primary Research

By integrating both secondary and primary research methodologies, we ensure that our database is comprehensive, accurate, and up-to-date. The combined process involves:

  • Merging historical data from secondary research with real-time data from primary research.
  • Conducting thorough data validation and cleansing to remove inconsistencies and errors.
  • Organizing data into a structured format that is easily accessible and usable for various applications.
  • Continuously monitoring and updating the database to reflect the latest developments and trends in the healthcare field.

Through this meticulous process, we create a final database tailored to each region and domain within the healthcare industry. This approach ensures that our clients receive reliable and relevant data, empowering them to make informed decisions and drive innovation in their respective fields.

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Last updated on: 13 February 2024
Updated by: Shivam Zalke

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