Indonesia Gram-Negative Infection Therapeutics Market Analysis

Indonesia Gram-Negative Infection Therapeutics Market Analysis


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The Indonesia Gram-Negative Infection Therapeutics Market was valued at $89.2 Mn in 2023 and is predicted to grow at a CAGR of 5.9% from 2023 to 2030 to $133.3 Mn by 2030. The main factors driving this market expansion include the rising prevalence of hospital-acquired infections (HAIs), increased demand due to the widespread overuse and misuse of antibiotics, and a fragmented healthcare system. Leading companies in this market in Indonesia include Kalbe Farma and Bio Farma, among others.

ID: IN10IDPH563 CATEGORY: Pharmaceuticals GEOGRAPHY: Indonesia AUTHOR: Aryan Patel

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Indonesia Gram-Negative Infection Therapeutics Market Executive Summary

The Indonesia Gram-Negative Infection Therapeutics Market was valued at $89.2 Mn in 2023 and is predicted to grow at a CAGR of 5.9% from 2023 to 2030 to $133.3 Mn by 2030.

Gram-negative bacteria are classified based on their cell wall structure and staining characteristics. They have a thin peptidoglycan cell wall and an outer membrane containing lipopolysaccharides. This unique structure makes them resistant to certain antibiotics and allows them to release endotoxins when disrupted. Gram-negative bacteria are characterized by their ability to stain pink or red under a microscope due to their lack of retention of the crystal violet dye used in gram staining. They are diverse, including pathogens such as Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, and Acinetobacter baumannii. These bacteria cause various infections, including pneumonia, sepsis, urinary tract infections, and wound infections, particularly in hospital settings.

Indonesia has a significant disease burden. The overall prevalence of HAIs in Southeast Asia is 21.6%, with Indonesia having the highest rate. Most of the HAIs in Indonesia are caused by gram-negative bacteria. Factors like increasing hospital-acquired infections (HAIs), rising demand due to widespread antibiotic overuse and misuse, and a fragmented healthcare system drive the market growth, whereas the lack of new therapies, limited healthcare infrastructure, and cost containment measures retrain the market.

Indonesia Gram Negative Infection Therapeutic Market Report 2023 to 2030

Market Dynamics

Market Growth Drivers

Increasing Hospital-Acquired Infections (HAIs): The overall prevalence of HAIs in Southeast Asia is 21.6%, with Indonesia having the highest rate. Limited resources for infection control measures further exacerbate the problem, further fuelling the demand for therapeutics.

Increase in demand due to widespread antibiotic overuse and misuse: The overuse and misuse of antibiotics, including easy access without prescription, has contributed to the growth of antimicrobial resistance (AMR) in Indonesia. This has created an urgent need for new antibiotics effective against drug-resistant gram-negative pathogens, thus increasing demand and driving the market.

Fragmented Healthcare System: Indonesia's decentralized public healthcare system with variable access to quality care has made the country vulnerable to AMR and infectious disease burdens. The lack of access to quality healthcare, vaccination, safe water, and sanitation leaves many susceptible to infection and dependent on antibiotics, thus driving the market.

Market Restraints

Lack of New Therapies: There is a lack of new antibiotics with novel mechanisms of action that are effective against drug-resistant gram-negative infections, which have high mortality rates. Despite the launch of some new antibiotics, the market remains heavily genericized, and cost-containment measures have limited the commercial success of new therapies, thus restraining the market.

Limited Healthcare Infrastructure: Indonesia's decentralized public healthcare system with variable access to quality care exacerbates the issue of AMR and infectious disease burdens, making it difficult to treat and manage gram-negative infections effectively, restraining market growth.

Cost Containment Measures: The market is heavily genericized, and cost-containment measures have limited the commercial success of new therapies, making it challenging for companies to invest in research and development of new treatments. This financial pressure makes it challenging for companies to invest in the research and development of new treatments, further restraining market expansion.

Regulatory Landscape and Reimbursement Scenario

The National Agency of Drug and Food Control (BPOM/NADFC) is the primary regulatory body responsible for guaranteeing the safety, quality, and effectiveness of pharmaceuticals in Indonesia. BPOM oversees the review process of drug registration applications and issues marketing authorizations as drug approvals, coordinating with the Ministry of Health (MOH) regarding regulatory affairs concerning drugs and pharmaceuticals.

The reimbursement scenario for gram-negative infection therapeutics in Indonesia involves a complex landscape with multiple players and factors influencing coverage. The BPOM and MOH regulate the market, while the Health Social Security Agency (BPJS) and the National Health Insurance (JKN) program are responsible for reimbursement. Companies must demonstrate the value proposition of their drugs, including clinical effectiveness and cost-effectiveness, to secure inclusion in the JKN formulary.

The reimbursement scenario is tiered, with full reimbursement for highly effective drugs targeting critical MDR infections, limited reimbursement for specific hospitals or patient groups based on cost considerations, and no initial reimbursement for costly drugs.

Competitive Landscape

Key Players

Here are some of the major key players in the Indonesia Gram-Negative Infection Therapeutics Market:

  • Kalbe Farma
  • Bio Farma
  • GlaxoSmithKline plc (GSK)
  • Pfizer Inc.
  • Sanofi-Aventis
  • Takeda Pharmaceutical Company Limited
  • Nektar Therapeutics
  • Baxter
  • Novartis
  • Sumitomo

1. Executive Summary
1.1 Disease Overview
1.2 Global Scenario
1.3 Country Overview
1.4 Healthcare Scenario in Country
1.5 Patient Journey
1.6 Health Insurance Coverage in Country
1.7 Active Pharmaceutical Ingredient (API)
1.8 Recent Developments in the Country

2. Market Size and Forecasting
2.1 Epidemiology of Disease
2.2 Market Size (With Excel & Methodology)
2.3 Market Segmentation (Check all Segments in Segmentation Section)

3. Market Dynamics
3.1 Market Drivers
3.2 Market Restraints

4. Competitive Landscape
4.1 Major Market Share

4.2 Key Company Profile (Check all Companies in the Summary Section)

4.2.1 Company
4.2.1.1 Overview
4.2.1.2 Product Applications and Services
4.2.1.3 Recent Developments
4.2.1.4 Partnerships Ecosystem
4.2.1.5 Financials (Based on Availability)

5. Reimbursement Scenario
5.1 Reimbursement Regulation
5.2 Reimbursement Process for Diagnosis
5.3 Reimbursement Process for Treatment

6. Methodology and Scope

Indonesia Gram-Negative Infection Therapeutics Market Segmentation

By Drug Types

  • Antibiotics
  • Combination Therapies
  • Adjunctive Therapies

By Infection Types

  • Urinary Tract Infections (UTIs)
  • Pneumonia
  • Bloodstream Infections (Bacteraemia)
  • Wound/Surgical Site Infections
  • Gastrointestinal Infections
  • Meningitis
  • Hospital-Acquired Infections (HAIs)
  • Respiratory Tract Infections (RTIs)
  • Other Infections

By Route of Administration

  • Oral
  • Parenteral (injections, intravenous)
  • Topical

By Distribution Channel

  • Hospitals
  • Clinics
  • Ambulatory Surgical Centres
  • Home Healthcare
  • Long-term Care Facilities
  • Community Health Centres

Insights10 will provide you with the reports within 10 key parameters which are:

  1. Market Overview
  2. Market Growth Drivers & Restraints
  3. Epidemiology of Disease Type
  4. Market Segmentation
  5. Market Share
  6. Competitive Landscape
  7. Key Company Profiles
  8. Healthcare Policies & Regulatory Framework
  9. Reimbursement Scenario
  10. Factors Driving Future Growth

Based on our many years of experience, we believe that these are the parameters that are critical to decision-making for business stakeholders. Our focused approach to developing reports focused on 10 key parameters, enabled us to arrive at the name “Insights10”.

 

Stage I: Market Data Collection

Primary Interviews: We have developed a network of experts, freelancers, and researchers across countries through which we engage with local experts to gather key data points and assumptions about each market. We also engage regularly with some of the best market research agencies such as Atheneum, GuidePoint, GLG, etc. to conduct surveys and interviews, and build intelligence. We have language translators as a part of our team, who between them can cover 30+ languages allowing us to extract better local insights.

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Data Sources: We have access to multiple highly reliable free and subscription data sources. We have many years of experience to understand which sources are more dependable for what and which to prefer for the reliable and latest information. The key sources of information include the following, but are not limited to:

 

 

Stage II: Market Data Analysis and Statistical Model

Market Trends: We generally look at macro parameters and micro indicators. The macro parameters include changes in government policies, demand and supply of the market, government intervention programs, and major market share. The micro indicators are GDP growth, market size, market volume, etc. We also understand nuances specific to each country like the US, Canada, India, Germany, etc., and have worked across 60+ countries and hence not only understand global trends but how these differ by country, how payment models, market structure, cultural parameters, etc. differ in each country.

Market Sizing and Analysis: Our expert data analytics team has created various market forecast models by employing the top-down approach i.e. starting with the large overall market and segmenting different areas and the bottom-up approach i.e. starting with population and epidemiology and rolling up based on spend, etc., estimating the size of the market, and distributing among the geographic and/or product segments.

The top-down approach is mainly used for new product forecasting and the bottom-up approach is used for demand estimation of any product for different countries summed up to form the total market. We are able to round off insights and build stronger forecasts because we always do both these methods and triangulate the final numbers.

The study on the market covers the analysis of the leading geographies such as Asia-Pacific, Africa, Europe, Middle East, North America, and  Latin America for the period of 2022 to 2030. The qualitative analysis covers the industry landscape and trends, market opportunities, competitive landscape, and policy and regulatory scenario, and the quantitative analysis covers different market estimates and forecasts.

Data Triangulation & Validation:

Data triangulation of various sources and results of the research are carried out by benchmarking with reliable sources such as industry statistics, statistical databases, and company-level averages, etc.

We make sure to finalize the numbers in alignment with the market research. Firstly, our internal experts ensure thorough validation and checking to ensure accurate and precise analysis and then validation is also done using a multiple-data analysis model. Two-level validation is done and entails the finalization of the report scope and the way of representation pattern.

 

 

Stage III: Interpretation and Presentation

Analysis & Interpretation: The information gathered is then analyzed and synthesized. The second series of interviews are done if necessary to check and validate. The future opportunities are analyzed by understanding product commercialization and many other factors. It also comprises the analysis of data discrepancies observed across various data sources. Information procured from secondary and primary results is then, interpreted by considering the following parameters: (a partial list)

  • Establishing market drivers and trends
  • Analyzing the regulatory landscape to understand future growth
  • Market Segment based analysis to obtain revenue/volume
  • ​Analyzing current needs and determining penetration to estimate the market

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Data curated from the analysis and interpretation are drawn to portray all in one consolidated report.

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The foreign exchange rates are calculated on the respective dates and for the respective regions covered in the study.

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Last updated on: 04 July 2024
Updated by: Dr. Purav Gandhi

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