Canada Pyruvate Kinase (PK) Deficiency Market Analysis

Canada Pyruvate Kinase (PK) Deficiency Market Analysis


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Canada Pyruvate Kinase (PK) deficiency market is projected to grow from $xx Mn in 2023 to $xx Mn by 2030, registering a CAGR of xx% during the forecast period of 2023 - 2030. The market for Pyruvate Kinase (PK) deficiency is growing rapidly as a result of increase in incidence and prevalence of disease, increased awareness about the disease, improved diagnostic techniques, advancements in treatment options, increase in research and development and rise in patient assistance programmes. Agios pharmaceuticals, Pfizer Inc., Sanofi, Novartis, Teva Pharmaceutical Industries Ltd, Green cross corporation are the top key market players operating in the global Pyruvate Kinase (PK) deficiency market.

ID: IN10CARD108 CATEGORY: Rare Diseases GEOGRAPHY: Canada AUTHOR: Gaurav Bhongale

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Canada Pyruvate Kinase (PK) Deficiency Market Analysis Summary

Canada Pyruvate Kinase (PK) Deficiency Market is valued at around $43.4 Mn in 2022 and is projected to reach $75.7 Mn by 2030, exhibiting a CAGR of 7.2% during the forecast period 2023-2030.

Pyruvate kinase deficiency is a rare genetic disorder in which deficiency of the enzyme pyruvate kinase occurs which is essential for the process of producing energy in red blood cells. The main cause for PK deficiency is autosomal recessive trait that is the child gets the disease from their family members. Hemolytic anaemia, a disorder brought on by this deficiency, is a condition where red blood cells live a shorter life. The severity of PK Deficiency can vary greatly from person to person, and the symptoms might appear at various ages. Fatigue and weakness, pale skin (pallor), shortness of breath, rapid heart rate, yellowing of the skin and eyes (jaundice), enlargement of the spleen, and gallstones are the common symptoms of this disease. Blood transfusion, bone marrow transplantation, splenectomy, phototherapy, folic acid supplementation, vitamin B supplementation, iron chelation (key-lay-shun), cholecystectomy and allogeneic hematopoietic stem cell transplantation (HSCT) are the different treatment options available. The main goal of treatment for PK Deficiency is to manage the symptoms and complications associated with the condition. Momenta Pharmaceuticals, Inc, Apellis Pharmaceuticals, F. Hoffmann-La Roche Ltd, Teva Pharmaceutical Industries Ltd, Zydus Cadila, Vertice Pharma, Concord Biotech, Alkem Labs, Dr. Reddy’s Laboratories Ltd, Jubilant Life Sciences Ltd, Strides Pharma Science Limited, Mylan N.V., Novartis AG, Sanofi, Rigel Pharmaceuticals Inc, Incyte Corporation, Alexion Pharmaceuticals are the top key global market players.

Market Dynamics

Market Drivers

An increase in the incidence and prevalence of disease, increased awareness about the disease, improved diagnostic techniques, advancements in treatment options, increase in research and development and rise in patient assistance and advocacy programmes are the main market growth drivers.

Market Restraints

Expensive treatment costs and a lack of skilled professionals are market growth restraints.

Key players

Alexion Pharmaceuticals Grifols Kedrion Biopharma Octapharma Baxter International Takeda Pharmaceutical Company Pfizer Sanofi BioMarin Pharmaceutical Novartis

1. Executive Summary
1.1 Disease Overview
1.2 Global Scenario
1.3 Country Overview
1.4 Healthcare Scenario in Country
1.5 Patient Journey
1.6 Health Insurance Coverage in Country
1.7 Active Pharmaceutical Ingredient (API)
1.8 Recent Developments in the Country

2. Market Size and Forecasting
2.1 Epidemiology of Disease
2.2 Market Size (With Excel & Methodology)
2.3 Market Segmentation (Check all Segments in Segmentation Section)

3. Market Dynamics
3.1 Market Drivers
3.2 Market Restraints

4. Competitive Landscape
4.1 Major Market Share

4.2 Key Company Profile (Check all Companies in the Summary Section)

4.2.1 Company
4.2.1.1 Overview
4.2.1.2 Product Applications and Services
4.2.1.3 Recent Developments
4.2.1.4 Partnerships Ecosystem
4.2.1.5 Financials (Based on Availability)

5. Reimbursement Scenario
5.1 Reimbursement Regulation
5.2 Reimbursement Process for Diagnosis
5.3 Reimbursement Process for Treatment

6. Methodology and Scope

Market Segmentations For Canada Pyruvate Kinase (PK) Deficiency market

By Population

  • Infants
  • Children
  • Adults

By Diagnosis

  • Bilirubin in the blood
  • Complete blood count (CBC), 
  • Genetic testing
  • Haptoglobin blood test
  • Osmotic fragility
  • Pyruvate kinase activity
  • Stool urobilinogen

By treatment

  • Blood transfusion
  • Bone marrow transplantation
  • Splenectomy
  • Phototherapy
  • Folic acid and vitamin B supplementation
  • Iron chelation (key-lay-shun)
  • Cholecystectomy
  • Allogeneic hematopoietic stem cell transplantation (HSCT)

By Distribution Channels:

  • Hospital pharmacies
  • Retail pharmacies
  • Online pharmacies
  • Others

By end users

  • hospitals
  • Research organizations
  • Clinics
  • Others

Methodology for Database Creation

Our database offers a comprehensive list of healthcare centers, meticulously curated to provide detailed information on a wide range of specialties and services. It includes top-tier hospitals, clinics, and diagnostic facilities across 30 countries and 24 specialties, ensuring users can find the healthcare services they need.​

Additionally, we provide a comprehensive list of Key Opinion Leaders (KOLs) based on your requirements. Our curated list captures various crucial aspects of the KOLs, offering more than just general information. Whether you're looking to boost brand awareness, drive engagement, or launch a new product, our extensive list of KOLs ensures you have the right experts by your side. Covering 30 countries and 36 specialties, our database guarantees access to the best KOLs in the healthcare industry, supporting strategic decisions and enhancing your initiatives.

How Do We Get It?

Our database is created and maintained through a combination of secondary and primary research methodologies.

1. Secondary Research

With many years of experience in the healthcare field, we have our own rich proprietary data from various past projects. This historical data serves as the foundation for our database. Our continuous process of gathering data involves:

  • Analyzing historical proprietary data collected from multiple projects.
  • Regularly updating our existing data sets with new findings and trends.
  • Ensuring data consistency and accuracy through rigorous validation processes.

With extensive experience in the field, we have developed a proprietary GenAI-based technology that is uniquely tailored to our organization. This advanced technology enables us to scan a wide array of relevant information sources across the internet. Our data-gathering process includes:

  • Searching through academic conferences, published research, citations, and social media platforms
  • Collecting and compiling diverse data to build a comprehensive and detailed database
  • Continuously updating our database with new information to ensure its relevance and accuracy

2. Primary Research

To complement and validate our secondary data, we engage in primary research through local tie-ups and partnerships. This process involves:

  • Collaborating with local healthcare providers, hospitals, and clinics to gather real-time data.
  • Conducting surveys, interviews, and field studies to collect fresh data directly from the source.
  • Continuously refreshing our database to ensure that the information remains current and reliable.
  • Validating secondary data through cross-referencing with primary data to ensure accuracy and relevance.

Combining Secondary and Primary Research

By integrating both secondary and primary research methodologies, we ensure that our database is comprehensive, accurate, and up-to-date. The combined process involves:

  • Merging historical data from secondary research with real-time data from primary research.
  • Conducting thorough data validation and cleansing to remove inconsistencies and errors.
  • Organizing data into a structured format that is easily accessible and usable for various applications.
  • Continuously monitoring and updating the database to reflect the latest developments and trends in the healthcare field.

Through this meticulous process, we create a final database tailored to each region and domain within the healthcare industry. This approach ensures that our clients receive reliable and relevant data, empowering them to make informed decisions and drive innovation in their respective fields.

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Last updated on: 04 July 2023
Updated by: Shivam Zalke

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