Canada Hemophilia A Therapeutics Market Report 2023 to 2030

Canada Hemophilia A Therapeutics Market Analysis

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Canada Hemophilia A Therapeutics Market is projected to grow from $xx Mn in 2023 to $xx Mn by 2030, registering a CAGR of xx% during the forecast period of 2023 - 2030. A lack of or failure with regard to clotting factor VIII characterises the rare inherited bleeding condition known as haemophilia A. It is the most prevalent form of haemophilia and primarily affects men, though it can also afflict women who carry the gene mutation. Hemophilia A market development goes beyond traditional markets, with a stronger emphasis on increasing access to care in developing markets. In areas where access to specialised care and therapies may be restricted, efforts are being made to improve diagnosis, treatment infrastructure, and pricing. Some of the notable companies operating in the Hemophilia A therapeutics market include BioMarin Pharmaceutical Inc, Bayer AG, Pfizer Inc., Novo Nordisk A/S, F. Hoffmann-La Roche Ltd., Shire (now part of Takeda Pharmaceutical Company Limited), CSL Behring LLC, Sanofi S.A., Grifols S.A. and Octapharma AG.

ID: IN10CARD031 CATEGORY: Rare Diseases GEOGRAPHY: Canada AUTHOR: Nipun Arora

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Canada Hemophilia A Therapeutics Market Analysis Summary

Canada Hemophilia A Therapeutics Market is valued at around $0.9 Mn in 2022 and is projected to reach $1.33 Mn by 2030, exhibiting a CAGR of 5% during the forecast period 2023-2030.

Due to a deficiency in factor VIII, haemophilia A is a rare genetic illness that affects a person's blood's capacity to clot. About one in 5,000 male newborns, each year are affected by haemophilia A, whereas females are less frequently affected. A hereditary mutation in the F8 gene—which codes for the production of clotting factor VIII—leads to haemophilia A. The mutation causes functional factor VIII to be produced insufficiently or not at all, which impairs blood clotting and prolongs bleeding. Bleeding episodes, which can include life-threatening haemorrhages, acute and persistent pain, permanent joint injury with a disability, and adverse effects on quality of life, can occur in people with haemophilia. Market development for haemophilia A goes beyond the conventional markets, with a stronger emphasis on increasing access to care in developing markets. In areas with potentially limited access to specialised care and therapies, efforts are being made to improve diagnosis, treatment infrastructure, and pricing. Sanofi S.A., Grifols S.A., Octapharma AG, BioMarin Pharmaceutical Inc., Bayer AG, Pfizer Inc., Novo Nordisk A/S, F. Hoffmann-La Roche Ltd., Shire (now a subsidiary of Takeda Pharmaceutical Company Limited), CSL Behring LLC, Novo Nordisk A/S, and Shire are a few of the well-known companies in the Hemophilia A therapeutics market.

Market Dynamics

Market Drivers

One of the main factors favourably affecting the market is the rising incidence of genetic disorders among people worldwide and the rising number of hemophilic patients. In addition, the increasing prevalence of preventative treatments to treat Hemophilia A and the increasing incidence of disease detection are providing lucrative growth prospects to top market players. In addition, government organisations in many nations are running a number of initiatives to raise awareness of the advantages of early diagnosis and implementing the right policies to support the early screening of newborns, which is encouraging the market. Additionally, because there are few treatment choices available, they are sponsoring R&D initiatives more and more. A positive market outlook is provided by the fact that top industry players are concentrating on introducing technologically cutting-edge diagnostic tools and therapies to improve the efficacy and accuracy of Hemophilia A treatment. The market is also expected to be driven by significant expenditures in the global expansion of specialist Hemophilia A treatment centres (HTCs).

Market Development

The US Food and Drug Administration (FDA) authorised Sanofi's ALTUVIIIO on February 22, 2023. The FDA has approved ALTUVIIIOTM, a novel class of factor VIII therapy for haemophilia A that provides considerable bleed protection, as a once-weekly regimen.

In individuals with severe haemophilia A, a phase III clinical study is being conducted to assess the safety and efficacy of valoctocogene roxaparvovec combined with preventive corticosteroids.

By 2028, Pfizer expects to have completed the Phase 3, Open-Label, Single-Arm Study to Assess the Efficacy and Safety of Recombinant AAV2/6 Human Factor VIII Gene Therapy in Adult Male Participants with Moderately Severe to Severe Hemophilia A(FVIII: C1 per cent).

Key players

BioMarin Pharmaceutical Inc CSL Behring Grifols SA Kedrion Biopharma SpA Novo Nordisk A/S Pfizer Inc Roche Holding AG Sanofi Shire plc Takeda Pharmaceutical Co Ltd

1. Executive Summary
1.1 Disease Overview
1.2 Global Scenario
1.3 Country Overview
1.4 Healthcare Scenario in Country
1.5 Patient Journey
1.6 Health Insurance Coverage in Country
1.7 Active Pharmaceutical Ingredient (API)
1.8 Recent Developments in the Country

2. Market Size and Forecasting
2.1 Epidemiology of Disease
2.2 Market Size (With Excel & Methodology)
2.3 Market Segmentation (Check all Segments in Segmentation Section)

3. Market Dynamics
3.1 Market Drivers
3.2 Market Restraints

4. Competitive Landscape
4.1 Major Market Share

4.2 Key Company Profile (Check all Companies in the Summary Section)

4.2.1 Company
4.2.1.1 Overview
4.2.1.2 Product Applications and Services
4.2.1.3 Recent Developments
4.2.1.4 Partnerships Ecosystem
4.2.1.5 Financials (Based on Availability)

5. Reimbursement Scenario
5.1 Reimbursement Regulation
5.2 Reimbursement Process for Diagnosis
5.3 Reimbursement Process for Treatment

6. Methodology and Scope

Market Segmentations For Canada Hemophilia A Therapeutics Market

By Therapy

Recombinant
Plasma-derived
Hormonal
Extended half-life

By Drugs

Desmopressin
Octocogalfa
Nonacogalfa

By End User

Hospital
Clinic
Pharmacy

Methodology for Database Creation

Our database offers a comprehensive list of healthcare centers, meticulously curated to provide detailed information on a wide range of specialties and services. It includes top-tier hospitals, clinics, and diagnostic facilities across 30 countries and 24 specialties, ensuring users can find the healthcare services they need.

Additionally, we provide a comprehensive list of Key Opinion Leaders (KOLs) based on your requirements. Our curated list captures various crucial aspects of the KOLs, offering more than just general information. Whether you're looking to boost brand awareness, drive engagement, or launch a new product, our extensive list of KOLs ensures you have the right experts by your side. Covering 30 countries and 36 specialties, our database guarantees access to the best KOLs in the healthcare industry, supporting strategic decisions and enhancing your initiatives.

How Do We Get It?

Our database is created and maintained through a combination of secondary and primary research methodologies.

1. Secondary Research

With many years of experience in the healthcare field, we have our own rich proprietary data from various past projects. This historical data serves as the foundation for our database. Our continuous process of gathering data involves:

Analyzing historical proprietary data collected from multiple projects.
Regularly updating our existing data sets with new findings and trends.
Ensuring data consistency and accuracy through rigorous validation processes.

With extensive experience in the field, we have developed a proprietary GenAI-based technology that is uniquely tailored to our organization. This advanced technology enables us to scan a wide array of relevant information sources across the internet. Our data-gathering process includes:

Searching through academic conferences, published research, citations, and social media platforms
Collecting and compiling diverse data to build a comprehensive and detailed database
Continuously updating our database with new information to ensure its relevance and accuracy

2. Primary Research

To complement and validate our secondary data, we engage in primary research through local tie-ups and partnerships. This process involves:

Collaborating with local healthcare providers, hospitals, and clinics to gather real-time data.
Conducting surveys, interviews, and field studies to collect fresh data directly from the source.
Continuously refreshing our database to ensure that the information remains current and reliable.
Validating secondary data through cross-referencing with primary data to ensure accuracy and relevance.

Combining Secondary and Primary Research

By integrating both secondary and primary research methodologies, we ensure that our database is comprehensive, accurate, and up-to-date. The combined process involves:

Merging historical data from secondary research with real-time data from primary research.
Conducting thorough data validation and cleansing to remove inconsistencies and errors.
Organizing data into a structured format that is easily accessible and usable for various applications.
Continuously monitoring and updating the database to reflect the latest developments and trends in the healthcare field.

Through this meticulous process, we create a final database tailored to each region and domain within the healthcare industry. This approach ensures that our clients receive reliable and relevant data, empowering them to make informed decisions and drive innovation in their respective fields.