US Hepatitis B Therapeutics Market


  • Type: Common Disease Area
  • Published : March 2021
  • Region: North America
  • Country: US
  • Report ID : 263

  • Format: PPT, PDF

US Hepatitis B Therapeutics Market: Segmented by Therapy Class (Nucleoside Analogs, Interferon-Alpha, Pegylated Interferon-Alpha and Nucleotide Analog Prodrugs), and Product (Vaccines and oral antiviral agents)- Market Analysis and Industry Forecast, 2019-2028


Report Overview

The US Hepatitis B therapeutics market is expected to grow at a CAGR of xx%, stood around at USD xx billion in 2019, and projected to reach USD xx billion by 2028 during the forecast period

Hepatitis B is a liver infection caused by the hepatitis B virus. Hepatitis B virus causes inflammation of the liver. In the US, an estimated 8,62,000 people were chronically infected in recent years. The rates of new Hepatitis B infection are highest among adults aged 40-49 years, reflecting low Hepatitis B vaccination coverage among adults at risk. The most common risk factor among people with new Hepatitis B infections is injecting drugs, related to the opioid crisis. A chronic Hepatitis B can cause severe implications like liver failure and liver cancer. The US government has made it mandatory for the people to go through the screening and monitoring since it’s not easily recognizable. It is expected that many innovative therapies that have shown positive results in clinical trials will occupy the market in upcoming years

Market Growth Drivers

The key factors driving the market growth of the Hepatitis B market are increased cases of cirrhosis deaths, increasing population of old age, increased healthcare expenditure, and urbanization leading to better screening and treatment. Some of the trends and developments include government initiatives, public awareness, research, and developments in therapeutics. The growth of the market can be hindered by management challenges, lack of diagnostic facilities, high cost of medical care, legal regulations, and competition in the market


1. US Hepatitis B Therapeutics Market Overview…………………………………………………
A. Market Size
2. Market Growth Drivers……………………………………………………..……………………….…..
A. Increased cases of cirrhosis deaths
B. Increased Government Initiatives, Public Awareness, Research, and Developments in Therapeutics
C. Increased healthcare expenditure and urbanization leading to better screening and treatment
3. Hepatitis B Major Therapeutics Market Segmentation……………………………………
A. By Therapy Class
I. Nucleoside analogues
II. Interferon-alpha
III. Pegylated interferon-alpha
IV. Nucleotide Analog Prodrugs
B. By Product
I. Vaccines
II. Oral anti-viral agents
4. Hepatitis B Major Therapeutics Market Drugs Market Share………..……..…..
A. Market Analysis, Insights and Forecast to 2028 by Revenue
5. Competitive Landscape………………………………………………………….………..
A. Major Players
B. Products in Pipeline
6. Key Company Profiles…………………………………………………………………….
A. Roche Company overview, Product & Services, Strategies & Financials
B. GlaxoSmithKline Company overview, Product & Services, Strategies & Financials
C. Vir Biotechnology Company profile, Product & Services, Strategies & Financials
7. Healthcare Policies and Regulatory Landscape…………………………………….…
A. Policy changes and Reimbursement scenario
8. Potential Growth Opportunities………………………………………………..…………
A. Advancements in drug development
9. Factors Driving Future Growth…………………………………………………………..
A. Key Industry Trends and Recent Developments in Hepatitis B Therapeutics Market
B. Future Opportunities
10. Conclusion




Market Segmentation

The Hepatitis B therapeutics market is segmented into the therapy type and product type

By Therapy Type:

The Chronic Hepatitis B market comprises approved therapies including interferon-alpha and pegylated interferon-alpha, nucleoside analogs (NA), and nucleotide analog prodrugs. INF-α was the first substance licensed to treat Chronic Hepatitis B. Lamivudine was the first NAs to be approved for the treatment of Chronic Hepatitis B, and Adefovir was the second. Tenofovir disoproxil fumarate (TDF) and Tenofovir alafenamide (TAF) as oral antiviral medications are options for CHB. TAF could treat Hepatitis B at less than one-tenth the dose of its predecessor, TDF

By Product Type:

Hepatitis B infection treated with either interferon or oral antiviral agents. These treatments expected to slow the progression of cirrhosis, reduce the incidence of liver cancer, and improve long-term survival. Among antiviral agents entecavir, tenofovir disoproxil fumarate and tenofovir alafenamide (TAF) recommended as the first choice of treatment regimens. Liver transplantation may be considered in cases of chronic liver failure. Hepatitis B vaccines (Recombivax HB, Engerix-B) are used to prevent Hepatitis B infection

Key Players

Companies like Vir Biotechnology, Nucorion Pharmaceuticals/Ligand Pharmaceuticals/Medpace, Vaccitech Limited, Antios Therapeutics, Altimmune, Hepion Pharmaceuticals, Enanta Pharmaceuticals, Enyo Pharma, Dicerna Pharmaceuticals, and GlaxoSmithKline are also investigating their candidates in the early stages of development. Roche is evaluating the role of RG7907 + RG7854 + NUC (Nucleos(t)ide) analogs combo in the treatment of hepatitis B patients

Research Methodology

Insights10 will provide you reports within 10 key parameters which are:

  1. Market overview
  2. Market growth drivers & restraints
  3. Epidemiology or disease type
  4. Market segmentation
  5. Market share
  6. Competitive landscape
  7. Key company profiles
  8. Healthcare policies & regulatory framework
  9. Reimbursement scenario
  10. Factors driving future growth

Based on our many years of experience, we believe that these are the parameters that are critical to decision making for business stakeholders. Our focused approach to develop reports focused on 10 key parameters, enabled us to arrive at the name “Insights10”.

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Market Sizing and Analysis: Our expert data analytics team has created various market forecast models by employing the top-down approach i.e. start with large overall market and segment different areas and bottom-up approach i.e. start with population and epidemiology and roll up based on spend, etc., estimating the size of the market, and distributing among the geographic and/or product segments.

The top-down approach mainly used for new product forecasting and bottom-up approach is used for demand estimation of any product for different countries summed up to form total market. We are able to round off insights and build stronger forecasts because we always do both these methods and triangulate the final numbers.

The study on the market covers the analysis of the leading geographies such as North America, Europe, Asia-Pacific, and Africa for the period of 2020 to 2028. The qualitative analysis covers the industry landscape and trends, market opportunities, competitive landscape and policy and regulatory scenario and the quantitative analysis covers different market estimates and forecasts.

Data Triangulation & Validation:

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We make sure to finalize the numbers in alignment to the market research. Firstly, our internal experts ensure thorough validation and checking to ensure the accurate and precise analysis and then validation is also done using multiple data analysis model.  Two level validation is done and entails finalization of report scope and to way of representation pattern.

Stage III: Interpretation and Presentation

Analysis & Interpretation: The information gathered is then analysed and synthesized. A second series of interviews are done if necessary to check and validate. The future opportunities are analysed by understanding product commercialization and many other factors. It also comprises the analysis of data discrepancies observed across various data sources. Information procured from secondary and primary results are then, interpreted by considering following parameters: (a partial list)

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  • Market Segment based analysis to obtain revenue / volume
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The foreign exchange rates are calculated on the respective dates and for the respective regions covered in the study.

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