US Chronic Lymphocytic Leukemia Therapeutics Market

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  • Type: Oncology area
  • Published : March 2021
  • Region: North America
  • Country: US
  • Report ID : 1089

  • Format: PPT, PDF

US Chronic Lymphocytic Leukemia Therapeutics Market Segmented by Therapy (Chemotherapy, Targeted Therapy, and Other) and by Route of Administration (Oral, Parenteral and Others)– Growth, Trends and Forecast, 2019-2028

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Report Overview

The US Chronic Lymphocytic Leukemia therapeutics market size stood at around USD XX billion in 2019 and is projected to reach USD xx billion by 2028, exhibiting a CAGR of xx% during the forecast period.

Chronic lymphocytic leukemia (CLL) is slow-growing cancer which begins in lymphocytes in the bone marrow and extends into the blood. It can even spread to lymph nodes and other organs such as spleen and liver. Chronic lymphocytic leukemia is divided into two types, B-cell chronic lymphocytic leukemia and T- cell chronic lymphocytic leukemia. Symptoms of chronic lymphocytic leukemia include enlarged lymph nodes, fever, fatigue and pain in the abdomen due to an enlarged spleen, weight loss, night sweats, frequent infections, and others

Chronic lymphocytic leukemia is the most prevalent adult leukemia in the Western world, accounting for approximately 30% of all leukemia’s diagnosed in the United States. Approximately 14,600 new cases of CLL are expected to be diagnosed in the United States in 2015. As per the higher cost, the per-patient lifetime cost of CLL treatment will increase from $147,000 to $604,000 (310% increase) as oral targeted therapies become the first-line treatment. For patients enrolled in Medicare, the corresponding total out-of-pocket cost will increase from $9,200 to $57,000 (520% increase)

Market Growth Drivers and Restraints

The major factors driving the growth of the market is the prevalence of various cancers and the rise in the geriatric population. An increase in the investment by the key players in the pharmaceutical R&D sector is expected to boost the growth of the chronic lymphocytic leukemia market throughout the forecasted period

Higher cost of the patented drugs and therapies is the key for market growth. The stringent government regulations and inadequate reimbursement policies in US might hamper the market growth. Higher pricing of drugs outpaces the therapies too. The number of people in the US living with chronic lymphocytic leukemia, which is a rare blood and bone marrow disease, is forecast to reach 199,000 in 2025, up from 128,000 five years ago, thanks to more effective treatment. But a higher-priced pill, which is used as a first-line therapy and taken indefinitely, will also outpace the cost of chemotherapy, which has a fixed duration for treatment

1. US Chronic Lymphocytic Leukemia Therapeutics Market Overview…….
A. Market Size
2. Market Growth Drivers and Restraints…………………………………………..
A. Market Drivers
I. Rise in prevalence of Chronic Lymphocytic Leukemia
II. Growing Geriatric Population
B. Market Restraints
I. Higher Cost of Patented Drugs and Therapies
3. Chronic Lymphocytic Leukemia by Diseases Indication
A. B-cell Chronic Lymphocytic Leukemia
B. T-cell Chronic Lymphocytic Leukemia
C. Natural Killer Chronic Lymphocytic Leukemia
4. Chronic Lymphocytic Leukemia Therapeutics Market Segmentation
A. By Therapy
I. Chemotherapy
II. Targeted Therapy
III. Other
B. By Route of Administration
I. Oral
II. Parenteral
5. Chronic Lymphocytic Leukemia Major Market Share
A. Market Analysis, Insights and Forecast by revenue
6. Competitive Landscape……………………………………………
A. Major Players
B. Products in Pipeline
7. Key Company Profiles……………………………………………
A. Novartis Company overview, Product & Services, Strategies & Financials
B. AstraZeneca Company overview, Product & Services, Strategies & Financials
C. AbbVie Company overview, Product & Services, Strategies & Financials
8. Healthcare Policies and Regulatory Landscape….…………
A. Policy Changes and Reimbursement Scenario
9. Factors Driving Market Growth…………………………………
A. Key Industry Developments
B. Future Opportunities
10. Conclusion

Market Segmentation

By Therapy:

On the basis of therapy, the market of chronic lymphocytic leukemia therapeutics market is segmented into chemotherapy, targeted therapy and other types of therapies. Chemotherapy accounts for its largest market share due to its access from decades and owing to the wide range of products that are available in the market contributing to the growth of the market

By Route of Administration:

On the basis of route of administration, the chronic lymphocytic leukemia market has been segmented into oral, parenteral and others

The parenteral route of administration segment is expected to witness the largest market revenue share in recent years and expected to do so over the forecast period. This dominance is due to their rapid absorbed and onset of action along with their availability in various routes such as intravenous, subcutaneous, intrathecal, or intramuscular routes according to the need of the patient

On the other hand, the drugs administered through the oral route experience the highest growth due to availability of various products in oral dosage forms like tablets and capsules along with combination of more than one drug which helps physicians coupled by the enhanced patient compliance due to their non-invasive nature and ease of administration without physicians assistance helps the oral dosage forms segment to grow at the highest rate during the forecast period

Top Major Players

The Chronic lymphocytic leukemia market is moderately competitive and consists of several major players. Few of the prominent players are developing the biosimilar to the existing chemotherapies while others are launching the generic products trending in the market. For instance, Ofatumumab (Novartis) was first approved by the FDA in 2009 for the treatment of chronic lymphocytic leukaemia (CLL) as an intravenous infusion with a high dose, administered by a healthcare provider. Furthermore, few key players are entering into partnerships to develop and increase their market position. Some of the companies which are currently dominating the market are Astra Zeneca, Novartis, and AbbVie Inc

Research Methodology

Insights10 will provide you reports within 10 key parameters which are:

  1. Market overview
  2. Market growth drivers & restraints
  3. Epidemiology or disease type
  4. Market segmentation
  5. Market share
  6. Competitive landscape
  7. Key company profiles
  8. Healthcare policies & regulatory framework
  9. Reimbursement scenario
  10. Factors driving future growth

Based on our many years of experience, we believe that these are the parameters that are critical to decision making for business stakeholders. Our focused approach to develop reports focused on 10 key parameters, enabled us to arrive at the name “Insights10”.

Our analysis methodology involves three critical stages:

Stage I: Market Data Collection

Primary Interviews: We have developed a network of experts, freelancers and researchers across countries through which we engage with local experts to gather key data points and assumptions around each market. We also engage regularly with some of the best market research agencies such as Atheneum, GuidePoint, GLG, etc. to conduct surveys and interviews, and build intelligence. We have language translators as a part of our team, who between them can cover 30+ languages allowing us to extract better local insights.

Secondary Data Collection: We have developed strong expertise and experience in secondary data collection methods for developing unique data sets and research material. We gather data from multiple reliable sources to maintain the high level of accuracy and consistency. The market data is analysed and forecasted using appropriate statistical and coherent models. The report offers an overall analysis of the market size, growth, market share as well as segment-level analysis of the specific market. Our report includes precise, to the point information related to the overall market, competition, growth drivers, challenges, regulatory updates, and competition.

Data Sources: We have access to multiple highly reliable free and subscription data sources. We have many years of experience to understand which sources are more dependable for what and which to prefer for the reliable and latest information. The key sources of information include the following, but are not limited to:

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  • Press Releases of Key Market Players

Stage II: Market Data Analysis and Statistical Model

Market Trends: We generally look at macro parameter and micro indicators. The macro parameters includes changes in government policies, demand and supply of the market, government intervention programs and major market share. The micro indicators GDP growth, market size, market volume etc. We also understand nuances specific to each country like US, Canada, India, Germany, etc. and have worked across 60+ countries and hence no only understand global trends, but how these differ by country, how payment models, market structure, cultural parameters, etc. differ in each country.

Market Sizing and Analysis: Our expert data analytics team has created various market forecast models by employing the top-down approach i.e. start with large overall market and segment different areas and bottom-up approach i.e. start with population and epidemiology and roll up based on spend, etc., estimating the size of the market, and distributing among the geographic and/or product segments.

The top-down approach mainly used for new product forecasting and bottom-up approach is used for demand estimation of any product for different countries summed up to form total market. We are able to round off insights and build stronger forecasts because we always do both these methods and triangulate the final numbers.

The study on the market covers the analysis of the leading geographies such as North America, Europe, Asia-Pacific, and Africa for the period of 2020 to 2028. The qualitative analysis covers the industry landscape and trends, market opportunities, competitive landscape and policy and regulatory scenario and the quantitative analysis covers different market estimates and forecasts.

Data Triangulation & Validation:

Data triangulation of various sources and results of the research are carried out by benchmarking with reliable sources such as industry statistics, statistical databases and the company level averages etc.

We make sure to finalize the numbers in alignment to the market research. Firstly, our internal experts ensure thorough validation and checking to ensure the accurate and precise analysis and then validation is also done using multiple data analysis model.  Two level validation is done and entails finalization of report scope and to way of representation pattern.

Stage III: Interpretation and Presentation

Analysis & Interpretation: The information gathered is then analysed and synthesized. A second series of interviews are done if necessary to check and validate. The future opportunities are analysed by understanding product commercialization and many other factors. It also comprises the analysis of data discrepancies observed across various data sources. Information procured from secondary and primary results are then, interpreted by considering following parameters: (a partial list)

  • Establishing market drivers and trends
  • Analyzing regulatory landscape to understand future growth
  • Market Segment based analysis to obtain revenue / volume
  • Analyzing current needs and determining penetration to estimate market

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Data curated from the analysis and interpretation are drawn to portray all in one consolidated report.

Presentation & Reporting: The market research report is presented in different forms such as charts by using a scientific approach for easy understanding. Historic, current and future analysis is provided for each market in terms of both value and volume. The size of the market is interpreted in the US Dollar value and the respective unit, based on the product, for volume consumptions.
The foreign exchange rates are calculated on the respective dates and for the respective regions covered in the study.

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