UK Fibrodysplasia Ossificans Progressiva (FOP) Market Analysis


  • Type: Rare Disease Area
  • Published : April 2021
  • Region: Europe
  • Country: UK
  • Report ID : 2574

  • Format: PPT, PDF

UK Fibrodysplasia Ossificans Progressiva Therapeutics Market: Segmented by Therapeutics, Route of Administration, and Distribution Channels – Size, Share, Impact, Growth, Trends, and Forecasts (2020 – 2028)

Published Date: June 2021

SKU: 2574 Categories: ,

Report Overview

The UK Fibrodysplasia Ossificans Progressiva (FOP) therapeutics market size stood at around USD xx billion in 2020 and is projected to reach USD xx billion by 2028, exhibiting a CAGR of xx% during the forecast period.

Fibrodysplasia Ossificans Progressiva also known as Myositis Ossificans Progressiva, is a rare genetic disorder in which muscle tissue and connective tissue such as tendons and ligaments are replaced by bone, forming bone outside the skeleton (extra-skeletal or heterotopic bone) which restricts the movement of that part of the body. This disorder most often starts in early childhood and it begins from the shoulders and neck, then it goes down through the rest of the body, as patients get older the bone replaces more and more of soft tissue and its progression vary from person to person.

In the UK there are about 40 individuals. Of an estimated 4000 affected individuals worldwide, there are approximately 900 known patients. This disorder affects both genders and all ethnicities. The prevalence in females with FOP (36 %) was almost fourfold greater than in males. This indicates a point prevalence of 0-61 x 10-6. A significant paternal age effect was evident for these new mutations in the UK.

Market Growth Drivers

The rise in market value can be attributed to the introduction of new treatments and therapies and development in the healthcare expenditure and the government support for the research and development for new and better treatment have fuelled the market growth.

Another market driver could be the rising demand for innovative treatments and cures. The market is also growing as people become more aware of FOP and how to treat it. The government’s assistance for research and development for new and improved treatments may help to boost the market’s growth. Increased healthcare spending will also help the market thrive. The introduction of novel therapies and an increase in cases of FOP are likely to be major drivers of the FOP therapeutics market.

Market Restraints

Delay in achieving the correct FOP diagnosis, lack of supporting regional infrastructure to patients and families, and the inability of individuals with the FOP in remote or underserved areas to reach the FOP community are the factors that are hampering the market.


1. UK FOP Therapeutics Market Overview………………………………………..
A. Market Size
2. Market Growth Drivers and Restraints………………………………………
Market Growth Drivers
A. Rising Demand of Novel Treatments and Therapies
B. Increase in Awareness Levels of Rare Diseases
C. Enhanced Government Support & Assistance
Market Restraints
A. Delay in Achieving the Correct Diagnosis
B. Lack of Proper Infrastructure
3. Major Types of Fibrodysplasia Ossificans Progressiva (FOP)……………
A. Classical Fibrodysplasia Ossificans Progressiva
B. Atypical Fibrodysplasia Ossificans Progressiva
C. Others
4. UK FOP Therapeutics Market Segmentation……………………………….
A. By Therapeutics
I. Corticosteroids
II. Non-steroidal Anti-inflammatory Drugs (NSAIDs)
III. Bisphosphonates
IV. Muscle Relaxants
V. Surgery
VI. Others
B. By Route of Administration
I. Oral
II. Topical
III. Parenteral
C. By Distribution Channels
I. Hospital Pharmacies
II. Retail Pharmacies
III. E-Pharmacies
5. Fibrodysplasia Ossificans Progressiva Major Products Market Share……
A. Market Analysis, Insights and Forecast – By Drug Revenue
6. Competitive Landscape…………………………………………………………………
A. Major Players
B. Products in Pipeline
7. Key Company Profiles………………………………………………………………….
A. AstraZeneca Company overview, Product & Services, Strategies & Financials
B. Pfizer Company overview, Product & Services, Strategies & Financials
C. Novartis Company overview, Product & Services, Strategies & Financials
8. Healthcare Policies and Regulatory Landscape………………………………
A. Policy changes and Reimbursement scenario
9. Factors Driving Future Growth…………………………………………………
A. New Trends and Development of FOP Therapeutics Market
B. Future Opportunities
10. Conclusion

Market Segmentation

By Therapeutics:

Based on therapeutics, the FOP therapeutics market can be segmented into classified into

  • Corticosteroids
  • Non-steroidal anti-inflammatory drugs (NSAIDs)
  • Bisphosphonates
  • Surgery
  • Others

The corticosteroids segment is expected to account for a major share of the FOP therapeutics market during the forecast period, owing to high usage of corticosteroids for the treatment of FOP that may help reduce the intense inflammation and tissue edema seen in the early stages of the disease.

By Route of Administration:

On the basis of route of administration, the FOP therapeutics market can be classified into

  • Oral
  • Topical
  • Parenteral

A drug AZD0530, also known as Saracatinib, is taken orally, as a once-daily dose, developed by AstraZeneca, could be used to treat FOP. Thus, Oral medications are mostly preferred for the treatment of FOP and hence, the segment is anticipated to hold a major share of the FOP therapeutics market during the forecast period.

By Distribution Channel:

In terms of distribution channel, the FOP therapeutics market can be categorized into

  • Retail pharmacies
  • Hospital pharmacies
  • e-pharmacies

The hospitals’ segment is anticipated to account for a major share of the market during the forecast period, due to a rise in the number of FOP treatments in hospitals.

Top 5 Major Players

The FOP therapeutics market is highly competitive, and the prominent players in the market have adopted various strategies to garner maximum market share. These include collaboration, product launch, partnership, acquisition, etc. Saracatinib is an oral drug to be taken, developed by AstraZeneca, could be used to treat FOP. Major key players operating in the UK market include AstraZeneca UK, Pfizer Inc., Novartis UK, Regeneron Pharmaceuticals Inc., and Blueprint Medicines Corporation.

Research Methodology

Insights10 will provide you reports within 10 key parameters which are:

  1. Market overview
  2. Market growth drivers & restraints
  3. Epidemiology or disease type
  4. Market segmentation
  5. Market share
  6. Competitive landscape
  7. Key company profiles
  8. Healthcare policies & regulatory framework
  9. Reimbursement scenario
  10. Factors driving future growth

Based on our many years of experience, we believe that these are the parameters that are critical to decision making for business stakeholders. Our focused approach to develop reports focused on 10 key parameters, enabled us to arrive at the name “Insights10”.

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Market Sizing and Analysis: Our expert data analytics team has created various market forecast models by employing the top-down approach i.e. start with large overall market and segment different areas and bottom-up approach i.e. start with population and epidemiology and roll up based on spend, etc., estimating the size of the market, and distributing among the geographic and/or product segments.

The top-down approach mainly used for new product forecasting and bottom-up approach is used for demand estimation of any product for different countries summed up to form total market. We are able to round off insights and build stronger forecasts because we always do both these methods and triangulate the final numbers.

The study on the market covers the analysis of the leading geographies such as North America, Europe, Asia-Pacific, and Africa for the period of 2020 to 2028. The qualitative analysis covers the industry landscape and trends, market opportunities, competitive landscape and policy and regulatory scenario and the quantitative analysis covers different market estimates and forecasts.

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We make sure to finalize the numbers in alignment to the market research. Firstly, our internal experts ensure thorough validation and checking to ensure the accurate and precise analysis and then validation is also done using multiple data analysis model.  Two level validation is done and entails finalization of report scope and to way of representation pattern.

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