UK Fibrodysplasia Ossificans Progressiva (FOP) Market Analysis

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  • Type: Rare Disease Area
  • Published : April 2021
  • Region: Europe
  • Country: UK
  • Report ID : 2574

  • Format: PPT, PDF

UK Fibrodysplasia Ossificans Progressiva Therapeutics Market: Segmented by Therapeutics, Route of Administration, and Distribution Channels – Size, Share, Impact, Growth, Trends, and Forecasts (2020 – 2028)

Published Date: June 2021

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SKU: 2574 Categories: ,

Report Overview

The UK Fibrodysplasia Ossificans Progressiva (FOP) therapeutics market size stood at around USD xx billion in 2020 and is projected to reach USD xx billion by 2028, exhibiting a CAGR of xx% during the forecast period.

Fibrodysplasia Ossificans Progressiva also known as Myositis Ossificans Progressiva, is a rare genetic disorder in which muscle tissue and connective tissue such as tendons and ligaments are replaced by bone, forming bone outside the skeleton (extra-skeletal or heterotopic bone) which restricts the movement of that part of the body. This disorder most often starts in early childhood and it begins from the shoulders and neck, then it goes down through the rest of the body, as patients get older the bone replaces more and more of soft tissue and its progression vary from person to person.

In the UK there are about 40 individuals. Of an estimated 4000 affected individuals worldwide, there are approximately 900 known patients. This disorder affects both genders and all ethnicities. The prevalence in females with FOP (36 %) was almost fourfold greater than in males. This indicates a point prevalence of 0-61 x 10-6. A significant paternal age effect was evident for these new mutations in the UK.

Market Growth Drivers

The rise in market value can be attributed to the introduction of new treatments and therapies and development in the healthcare expenditure and the government support for the research and development for new and better treatment have fuelled the market growth.

Another market driver could be the rising demand for innovative treatments and cures. The market is also growing as people become more aware of FOP and how to treat it. The government’s assistance for research and development for new and improved treatments may help to boost the market’s growth. Increased healthcare spending will also help the market thrive. The introduction of novel therapies and an increase in cases of FOP are likely to be major drivers of the FOP therapeutics market.

Market Restraints

Delay in achieving the correct FOP diagnosis, lack of supporting regional infrastructure to patients and families, and the inability of individuals with the FOP in remote or underserved areas to reach the FOP community are the factors that are hampering the market.

TABLE OF CONTENTS

1. UK FOP Therapeutics Market Overview………………………………………..
A. Market Size
2. Market Growth Drivers and Restraints………………………………………
Market Growth Drivers
A. Rising Demand of Novel Treatments and Therapies
B. Increase in Awareness Levels of Rare Diseases
C. Enhanced Government Support & Assistance
Market Restraints
A. Delay in Achieving the Correct Diagnosis
B. Lack of Proper Infrastructure
3. Major Types of Fibrodysplasia Ossificans Progressiva (FOP)……………
A. Classical Fibrodysplasia Ossificans Progressiva
B. Atypical Fibrodysplasia Ossificans Progressiva
C. Others
4. UK FOP Therapeutics Market Segmentation……………………………….
A. By Therapeutics
I. Corticosteroids
II. Non-steroidal Anti-inflammatory Drugs (NSAIDs)
III. Bisphosphonates
IV. Muscle Relaxants
V. Surgery
VI. Others
B. By Route of Administration
I. Oral
II. Topical
III. Parenteral
C. By Distribution Channels
I. Hospital Pharmacies
II. Retail Pharmacies
III. E-Pharmacies
5. Fibrodysplasia Ossificans Progressiva Major Products Market Share……
A. Market Analysis, Insights and Forecast – By Drug Revenue
6. Competitive Landscape…………………………………………………………………
A. Major Players
B. Products in Pipeline
7. Key Company Profiles………………………………………………………………….
A. AstraZeneca Company overview, Product & Services, Strategies & Financials
B. Pfizer Company overview, Product & Services, Strategies & Financials
C. Novartis Company overview, Product & Services, Strategies & Financials
8. Healthcare Policies and Regulatory Landscape………………………………
A. Policy changes and Reimbursement scenario
9. Factors Driving Future Growth…………………………………………………
A. New Trends and Development of FOP Therapeutics Market
B. Future Opportunities
10. Conclusion

Market Segmentation

By Therapeutics:

Based on therapeutics, the FOP therapeutics market can be segmented into classified into

  • Corticosteroids
  • Non-steroidal anti-inflammatory drugs (NSAIDs)
  • Bisphosphonates
  • Surgery
  • Others

The corticosteroids segment is expected to account for a major share of the FOP therapeutics market during the forecast period, owing to high usage of corticosteroids for the treatment of FOP that may help reduce the intense inflammation and tissue edema seen in the early stages of the disease.

By Route of Administration:

On the basis of route of administration, the FOP therapeutics market can be classified into

  • Oral
  • Topical
  • Parenteral

A drug AZD0530, also known as Saracatinib, is taken orally, as a once-daily dose, developed by AstraZeneca, could be used to treat FOP. Thus, Oral medications are mostly preferred for the treatment of FOP and hence, the segment is anticipated to hold a major share of the FOP therapeutics market during the forecast period.

By Distribution Channel:

In terms of distribution channel, the FOP therapeutics market can be categorized into

  • Retail pharmacies
  • Hospital pharmacies
  • e-pharmacies

The hospitals’ segment is anticipated to account for a major share of the market during the forecast period, due to a rise in the number of FOP treatments in hospitals.

Top 5 Major Players

The FOP therapeutics market is highly competitive, and the prominent players in the market have adopted various strategies to garner maximum market share. These include collaboration, product launch, partnership, acquisition, etc. Saracatinib is an oral drug to be taken, developed by AstraZeneca, could be used to treat FOP. Major key players operating in the UK market include AstraZeneca UK, Pfizer Inc., Novartis UK, Regeneron Pharmaceuticals Inc., and Blueprint Medicines Corporation.

Research Methodology

Insights10 will provide you reports within 10 key parameters which are:

  1. Market overview
  2. Market growth drivers & restraints
  3. Epidemiology or disease type
  4. Market segmentation
  5. Market share
  6. Competitive landscape
  7. Key company profiles
  8. Healthcare policies & regulatory framework
  9. Reimbursement scenario
  10. Factors driving future growth

Based on our many years of experience, we believe that these are the parameters that are critical to decision making for business stakeholders. Our focused approach to develop reports focused on 10 key parameters, enabled us to arrive at the name “Insights10”.

Our analysis methodology involves three critical stages:

Stage I: Market Data Collection

Primary Interviews: We have developed a network of experts, freelancers and researchers across countries through which we engage with local experts to gather key data points and assumptions around each market. We also engage regularly with some of the best market research agencies such as Atheneum, GuidePoint, GLG, etc. to conduct surveys and interviews, and build intelligence. We have language translators as a part of our team, who between them can cover 30+ languages allowing us to extract better local insights.

Secondary Data Collection: We have developed strong expertise and experience in secondary data collection methods for developing unique data sets and research material. We gather data from multiple reliable sources to maintain the high level of accuracy and consistency. The market data is analysed and forecasted using appropriate statistical and coherent models. The report offers an overall analysis of the market size, growth, market share as well as segment-level analysis of the specific market. Our report includes precise, to the point information related to the overall market, competition, growth drivers, challenges, regulatory updates, and competition.

Data Sources: We have access to multiple highly reliable free and subscription data sources. We have many years of experience to understand which sources are more dependable for what and which to prefer for the reliable and latest information. The key sources of information include the following, but are not limited to:

  • Statistical Databases
  • Company Websites/Annual Reports
  • Trade Publications
  • Online Databases
  • Published Research Reports
  • Whitepapers
  • Press Releases of Key Market Players

Stage II: Market Data Analysis and Statistical Model

Market Trends: We generally look at macro parameter and micro indicators. The macro parameters includes changes in government policies, demand and supply of the market, government intervention programs and major market share. The micro indicators GDP growth, market size, market volume etc. We also understand nuances specific to each country like US, Canada, India, Germany, etc. and have worked across 60+ countries and hence no only understand global trends, but how these differ by country, how payment models, market structure, cultural parameters, etc. differ in each country.

Market Sizing and Analysis: Our expert data analytics team has created various market forecast models by employing the top-down approach i.e. start with large overall market and segment different areas and bottom-up approach i.e. start with population and epidemiology and roll up based on spend, etc., estimating the size of the market, and distributing among the geographic and/or product segments.

The top-down approach mainly used for new product forecasting and bottom-up approach is used for demand estimation of any product for different countries summed up to form total market. We are able to round off insights and build stronger forecasts because we always do both these methods and triangulate the final numbers.

The study on the market covers the analysis of the leading geographies such as North America, Europe, Asia-Pacific, and Africa for the period of 2020 to 2028. The qualitative analysis covers the industry landscape and trends, market opportunities, competitive landscape and policy and regulatory scenario and the quantitative analysis covers different market estimates and forecasts.

Data Triangulation & Validation:

Data triangulation of various sources and results of the research are carried out by benchmarking with reliable sources such as industry statistics, statistical databases and the company level averages etc.

We make sure to finalize the numbers in alignment to the market research. Firstly, our internal experts ensure thorough validation and checking to ensure the accurate and precise analysis and then validation is also done using multiple data analysis model.  Two level validation is done and entails finalization of report scope and to way of representation pattern.

Stage III: Interpretation and Presentation

Analysis & Interpretation: The information gathered is then analysed and synthesized. A second series of interviews are done if necessary to check and validate. The future opportunities are analysed by understanding product commercialization and many other factors. It also comprises the analysis of data discrepancies observed across various data sources. Information procured from secondary and primary results are then, interpreted by considering following parameters: (a partial list)

  • Establishing market drivers and trends
  • Analyzing regulatory landscape to understand future growth
  • Market Segment based analysis to obtain revenue / volume
  • Analyzing current needs and determining penetration to estimate market

Insights: Our reports deliver actionable insights backed with supporting facts and figures to assist you in achieving exemplary growth. Our in-depth analyses are interspersed with relevant insights and statistics to offer an executive-level view of a given market. The description helps in correlating many minor factors affecting the market and its impact to the different segments within the market.
Data curated from the analysis and interpretation are drawn to portray all in one consolidated report.

Presentation & Reporting: The market research report is presented in different forms such as charts by using a scientific approach for easy understanding. Historic, current and future analysis is provided for each market in terms of both value and volume. The size of the market is interpreted in the US Dollar value and the respective unit, based on the product, for volume consumptions.
The foreign exchange rates are calculated on the respective dates and for the respective regions covered in the study.

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