UK Autoimmune Hemolytic Anemia (AIHA) Market Analysis

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  • Type: Rare Disease Area
  • Published : April 2021
  • Region: Europe
  • Country: UK
  • Report ID : 2577

  • Format: PPT, PDF

UK Autoimmune Haemolytic Anaemia Therapeutics Market: Segmented by Diagnosis, Treatment, Distribution Channels, and End Users – Size, Share, Impact, Growth, Trends, and Forecasts (2020 – 2028)

Published Date: June 2021

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SKU: 2577 Categories: ,

Report Overview

The UK Autoimmune Haemolytic Anaemia (AIHA) Therapeutics market size stood at around USD xx billion in 2020 and is projected to reach USD xx billion by 2028, exhibiting a CAGR of xx% during the forecast period.

AIHA is an autoimmune disorder characterised by the premature destruction of healthy red blood cells (RBCs) by auto-antibodies. It is a common disorder directed against self RBCs which can be idiopathic (primary) or secondary. In w-AIHA, the autoantibodies react optimally with the RBCs at 37C. Normally, red blood cells live in the body for 100 to 120 days. However, in severe cases of AIHA, the cells may remain only for a few days. In children, it is a rare condition that is usually temporary. In some adults, however, AIHA can be a long-term condition that returns frequently. AIHA can develop rapidly or over time.

AIHA is a decompensated acquired haemolysis caused by the host’s immune system acting against its own red cell antigens. The incidence is 1 per 100,000/year and approximately half of the cases are secondary to an associated disorder. Serologically, cases are divided into warm, cold (cold haemagglutinin disease and paroxysmal cold haemoglobinuria) or mixed AIHA.

Market Growth Drivers

The AIHA market is primarily driven by an increase in the use of drugs, such as corticosteroids, for patients with autoimmune haemolytic anaemia. The prevalence of AIHA is rising due to the rapidly increasing geriatric population. The geriatric population is more vulnerable to diseases due to poor immunity, hence fosters market growth.

The steady increase in the use of immunoglobulin for the treatment of off-label indications is expected to drive the market during the forecast period. Technological improvements in the production and purification methods of intravenous immunoglobulins (IVIG) have made these safer and free from protein, viral, or any other contaminants. This has increased clinician preference for the usage of IVIG. This, in turn, boosts the market growth during the forecast period.

The cost of plasma collection and manufacturing processes is high as compared to materials and processes used in the manufacture of traditional pharmaceutical products. Moreover, being a blood-derived component, highly sophisticated collection, purification, and storage methods are required for IVIG products.

Market Restraints

Due to fewer market players and the time gap between plasma collection and getting the product in the market, IVIG production becomes a tedious and time-consuming process, if not managed properly can hamper the IVIG, thus, in turn, the IVIG market during the forecast period.

TABLE OF CONTENTS

1. UK AIHA Therapeutics Market Overview……………………………………….
A. Market Size
2. Market Growth Drivers and Restraints……………………………………….…
Market Growth Drivers
A. Rise in Prevalence and Incidence of Autoimmune Haemolytic Anaemia
B. Technological Advancement Boosts the Market Growth
Market Restraints
A. High Cost of Treatment
B. Supply Demand Gaps Hamper the Market Growth
3. Major Types of AIHA…………………………………………………………………………
A. Primary AIHA
B. Secondary AIHA
C. Warm AIHA
D. Cold AIHA
E. Mixed AIHA
4. AIHA Therapeutics Market Segmentation…………………………………
A. By Diagnosis
I. Coomb’s Test
II. Bilirubin Test
III. Haptoglobin Test
IV. Reticulocyte Count
V. Peripheral Smear
VI. Cold Agglutinin Titre
VII. Others
B. By Treatment
I. Corticosteroids
II. Intravenous Immunoglobulins (IVIG)
III. Monoclonal Antibodies
IV. Immunosuppressants
V. Blood Transfusion
VI. Splenectomy (Surgery)
VII. Others
C. By Distribution Channels
I. Retail Pharmacies
II. Hospital Pharmacies
III. Online Pharmacies
D. By End Users
I. Hospitals and Clinics
II. Homecare
III. Speciality Centres
IV. Others
5. AIHA Major Drugs Market Share………………………………
A. Market Analysis, Insights and Forecast – By Revenue Type
6. Competitive Landscape…………………………………………………………………
A. Major Players
B. Products in Pipeline
7. Key Company Profiles………………………………………………………………….
A. Rigel Company overview, Product & Services, Strategies & Financials
B. Momenta Company overview, Product & Services, Strategies & Financials
C. Apellis Company overview, Product & Services, Strategies & Financials
D. Alexion Company overview, Product & Services, Strategies & Financials
E. Immunovant Company overview, Product & Services, Strategies & Financials
8. Healthcare Policies and Regulatory Landscape……………………………
A. Policy changes and Reimbursement scenario
9. Factors Driving Future Growth………………………………………………
A. New Trends and Development of AIHA Therapeutics Market
B. Future Opportunities
10. Conclusion

Market Segmentation

By Diagnosis:

Based on the diagnosis, the AIHA market is segregated into

  • Coomb’s test
  • Bilirubin test
  • Haptoglobin test
  • Reticulocyte count
  • Peripheral smear
  • Cold agglutinin titre
  • Others

A low red blood cell count, low haemoglobin and haematocrit levels are signs of anaemia; thus, physicians advise AIHA patients to diagnose by these tests to confirm the disease.

By Treatment:

On the basis of treatment, the AIHA treatment market can be divided into

  • Corticosteroids
  • Intravenous Immunoglobulins (IVIG)
  • Monoclonal Antibodies
  • Immunosuppressants
  • Blood Transfusion
  • Splenectomy (Surgery)
  • Others

The corticosteroids such as hydrocortisone or prednisone, IVIG, monoclonal antibodies such as rituximab and immunosuppressants like azathioprine and cyclophosphamide as well. The corticosteroids segment is anticipated to dominate the AIHA market during the forecast period due to an increase in the usage of corticosteroids for the treatment of autoimmune haemolytic anaemia.

By Distribution Channels:

In terms of distribution channels, the AIHA treatment market has been bifurcated into

  • Hospital pharmacies
  • Retail pharmacies
  • Online pharmacies

The hospital pharmacies segment is likely to account for a major share of the autoimmune haemolytic anaemia market during the forecast period due to a large number of AIHA patients treated in hospitals.

By End Users:

As per the end-user, the AIHA treatment market has been segmented into

  • Hospitals
  • Homecare
  • Speciality centres
  • Others

One-third of patients suffered from AIHA treated at the hospitals in the UK. Thus, the hospitals’ segment commands the largest market share in terms of value during the forecast period.

Top Major Players

The major key players operating in UK AIHA treatment markets are Rigel Pharmaceuticals Inc., Momenta Pharmaceuticals, Apellis Pharmaceuticals Inc, Alexion Pharmaceuticals, and Immunovant Sciences. The approved drugs are Fostamatinib, M-281, APL-2, ALXN1830, are IMVT-1401 are the approved drugs by the companies respectively.

Research Methodology

Insights10 will provide you reports within 10 key parameters which are:

  1. Market overview
  2. Market growth drivers & restraints
  3. Epidemiology or disease type
  4. Market segmentation
  5. Market share
  6. Competitive landscape
  7. Key company profiles
  8. Healthcare policies & regulatory framework
  9. Reimbursement scenario
  10. Factors driving future growth

Based on our many years of experience, we believe that these are the parameters that are critical to decision making for business stakeholders. Our focused approach to develop reports focused on 10 key parameters, enabled us to arrive at the name “Insights10”.

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The top-down approach mainly used for new product forecasting and bottom-up approach is used for demand estimation of any product for different countries summed up to form total market. We are able to round off insights and build stronger forecasts because we always do both these methods and triangulate the final numbers.

The study on the market covers the analysis of the leading geographies such as North America, Europe, Asia-Pacific, and Africa for the period of 2020 to 2028. The qualitative analysis covers the industry landscape and trends, market opportunities, competitive landscape and policy and regulatory scenario and the quantitative analysis covers different market estimates and forecasts.

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We make sure to finalize the numbers in alignment to the market research. Firstly, our internal experts ensure thorough validation and checking to ensure the accurate and precise analysis and then validation is also done using multiple data analysis model.  Two level validation is done and entails finalization of report scope and to way of representation pattern.

Stage III: Interpretation and Presentation

Analysis & Interpretation: The information gathered is then analysed and synthesized. A second series of interviews are done if necessary to check and validate. The future opportunities are analysed by understanding product commercialization and many other factors. It also comprises the analysis of data discrepancies observed across various data sources. Information procured from secondary and primary results are then, interpreted by considering following parameters: (a partial list)

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