South Korea Spinal Muscular Atrophy (SMA) Therapeutics Market Analysis


  • Type: Rare Disease Area
  • Published : June 2021
  • Region: Asia
  • Country: South Korea
  • Report ID : 4876

  • Format: PPT, PDF

South Korea Spinal Muscular Atrophy (SMA) Therapeutics Market: Segmented By Disease Type (Werdnig- Hoffman Disease, Infant SMA, Kugelberg- Welander Disease, and Adult SMA), By Drugs Used (Nusinersen, Onasemnogene Abeparvovec and Others) and By Distribution Channels (Hospital Pharmacy, Retail Pharmacy and Online Pharmacy)- Trends and Forecasts (2019 – 2028)

SKU: 4876 Categories: ,

Report Overview

The South Korea Spinal Muscular Atrophy (SMA) Therapeutics market size stood at around USD xx billion in 2019 and is projected to reach xx billion by 2028, exhibiting a CAGR of around 5.2% during the forecast period.

Spinal Muscular Atrophy (SMA) is a genetic neuromuscular disease characterized by muscle atrophy and weakness. The disease generally manifests early in life and is the leading genetic cause of death in infants and toddlers. SMA is caused by defects in the Survival Motor Neuron 1 (SMN1) gene that encodes the SMN protein. The SMN protein is critical to the health and survival of the nerve cells in the spinal cord responsible for muscle contraction (motor neurons). It is one of the most common rare disease. Spinal muscular atrophy affects 1 in 6,000 to 1 in 10,000 people.

The genetics of SMA provides a unique opportunity for therapeutic development. SMN2 also makes SMN protein, but at greatly reduced efficiency, leading to lower-than-normal levels of the protein. SMN2 provides an attractive target for developing SMA therapeutics, and the majority of drug development  efforts in the field are focused on increasing SMN protein production from this gene.

Market Drivers

Initiatives undertaken by various public, as well as non-profit, organizations for creating awareness regarding SMA is driving the market growth. Increase in R&D investment by major companies will boost the market growth in the forecast period. Granting of various drug designation to novel drugs is also accelerating the market growth for spinal muscular atrophy treatment.

High cost of treatment for spinal muscular atrophy is hindering the market growth. Lack of experienced professionals and less adoption rate of spinal muscular atrophy treatment options is restraining the market growth.

1. South Korea Spinal Muscular Atrophy (SMA) Therapeutics Market Overview……………………………….
A. Market Size
2. Market Growth Drivers………………………………………………………………….
A. Increase in Awareness Regarding SMA
B. Increase in R&D Investment by Major Companies
3. Epidemiology of Spinal Muscular Atrophy (SMA)…………………………………..
A. Prevalence
B. Incidence
4. Spinal Muscular Atrophy (SMA) Therapeutics Market Segmentation……
A. Disease Type
I. Werdnig- Hoffman Disease
II. Infant SMA
III. Kugelberg- Welander Disease
IV. Adult SMA
B. Drugs Used
I. Nusinersen
II. Onasemnogene
III. Abeparvovec
IV. Others
C. Distribution Channels
I. Hospital Pharmacy
II. Retail Pharmacy
III. Online Pharmacy
5. Spinal Muscular Atrophy (SMA) Therapeutics Major Products Market Share…………….
A. Market Analysis, Insights and Forecast – By Revenue
6. Competitive Landscape…………………………………………………………………
A. Major Players
B. Products in Pipeline
7. Key Company Profiles………………………………………………………………….
A. Biogen Company Overview, Product & Services, Strategies & Financials
B. Roche Company Overview, Product & Services, Strategies & Financials
C. Novartis Company Overview, Product & Services, Strategies & Financials
8. Healthcare Policies and Regulatory Landscape……………………………
A. Policy changes and Reimbursement scenario
9. Factors Driving Future Growth…………………………………………………
A. New Trends and Development of Spinal Muscular Atrophy (SMA) Therapeutics Market
B. Future Opportunities
10. Conclusion

Market Segmentation

By Disease Type:

On the basis of disease type market is segmented as Werdnig- Hoffman Disease, infant SMA, Kugelberg- Welander Disease and adult SMA.

By Drugs Used:

According to the drugs used market is segmented as nusinersen, onasemnogene, abeparvovec and others.

By Distribution Channel:

South Korea’s SMA therapeutics market is segmented into hospital pharmacy, retail pharmacy, online pharmacy, and others on the basis of distribution channel.


Top Players

Some of the major players in market are Allen & Hanburys, AveXis, Biogen, GlaxoSmithKline, Kowa, Novartis, PTC Therapeutics, Rhone-Poulenc Rorer, Roche, Sanofi, and others.

Pipeline products launching from 2020 onwards are expected to capture significant market share. Key opinion leaders express excitement regarding the potential of the late-stage pipeline to expand access to therapy and address key unmet needs. In particular, Novartis’ gene therapy Zolgensma (Onasemnogene abeparvovec-xioi) represents a potentially transformative treatment option as it is administered by a one-time intravenous infusion. Additionally, the launch of Roche’s Risdiplam, an SMN2 splicing modifier, is also eagerly anticipated owing to the drug’s convenient oral administration route.

Research Methodology

Insights10 will provide you reports within 10 key parameters which are:

  1. Market overview
  2. Market growth drivers & restraints
  3. Epidemiology or disease type
  4. Market segmentation
  5. Market share
  6. Competitive landscape
  7. Key company profiles
  8. Healthcare policies & regulatory framework
  9. Reimbursement scenario
  10. Factors driving future growth

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The study on the market covers the analysis of the leading geographies such as North America, Europe, Asia-Pacific, and Africa for the period of 2020 to 2028. The qualitative analysis covers the industry landscape and trends, market opportunities, competitive landscape and policy and regulatory scenario and the quantitative analysis covers different market estimates and forecasts.

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