South Korea Paroxysmal Noctural Hemglobinuria (PNH) Market Analysis


  • Type: Rare Disease Area
  • Published : June 2021
  • Region: Asia
  • Country: South Korea
  • Report ID : 4935

  • Format: PPT, PDF

South Korea Paroxysmal Nocturnal Haemoglobinuria (PNH) Market: Segmented By Treatment (Medication, Supplements, Blood Transfusion, Bone Marrow Transplant and Others), By Drugs (Eculizumab, Ravulizumab and Others), and By Route of Administration (Oral and Parenteral)- Growth, Trends and Forecasts (2019 – 2028)

SKU: 4935 Categories: ,

Report Overview

The South Korea Paroxysmal Nocturnal Haemoglobinuria (PNH) Market size stood at around USD xx billion in 2019 and is projected to reach xx billion by 2028, exhibiting a CAGR of around xx% during the forecast period.

Paroxysmal nocturnal haemoglobinuria (PNH) is a rare acquired, life-threatening disease of the blood. PNH occurs when mutations of a gene called PIG-A occur in a bone marrow stem cell. The disease is characterized by destruction of red blood cells, blood clots, and impaired bone marrow function. PNH affects 1-1.5 persons per million of the population and is primarily a disease of younger adults. The median age of diagnosis is 35-40 years of age, with occasional cases diagnosed in childhood or adolescence. PNH is closely related to aplastic anaemia. In fact, up to 30% of newly diagnosed cases of PNH evolve from aplastic anaemia. The median survival after diagnosis is 10 years; however, some patients can survive for decades with only minor symptoms.

Market Drivers

Emergence of biologics that target causal haemolytic defect or abnormal hematopoietic stem cell will boosting the market growth. For instance, Samsung Bioepis, a joint venture between Samsung Biologics and Biogen, will begin a clinical study to develop a biosimilar for Soliris used to treat PNH. Other factors like increasing prevalence of blood disorders, high unmet demand for drugs, rise in investment for the development of novel drugs are also driving the market growth.

1. South Korea Paroxysmal Nocturnal Haemoglobinuria (PNH) Market Overview…
A. Market Size
2. Market Growth Drivers………………………………………………….
A. Increasing Prevalence Of Blood Disorders
B. Emergence Of Biologics
3. Types of Paroxysmal Nocturnal Haemoglobinuria (PNH) ………………………
A. Classical PNH
B. PNH in Context Of Other Primary Bone Marrow Disorders
C. Subclinical PNH
4. Paroxysmal Nocturnal Haemoglobinuria (PNH) Market Segmentation…
A. Treatment
I. Medication
II. Supplements
III. Blood Transfusion
IV. Bone Marrow Transplant
V. Others
B. Drugs
I. Eculizumab
II. Ravulizumab
III. Others
C. Route Of Administration
I. Oral
II. Parenteral
5. Paroxysmal Nocturnal Haemoglobinuria (PNH) Products Market Share…
A. Market Analysis, Insights and Forecast – By Revenue
6. Competitive Landscape……………………………………………………
A. Major Players
B. Products in Pipeline
7. Key Company Profiles…………………………………………….
A. Alexion Pharmaceuticals Company Overview, Product & Services, Strategies & Financials
B. Samsung Bioepis Company Overview, Product & Services, Strategies & Financials
C. Isu Abxis Company Overview, Product & Services, Strategies & Financials
8. Healthcare Policies and Regulatory Landscape………………………
A. Policy changes and Reimbursement scenario
9. Factors Driving Future Growth…………………………………………
A. New Trends and Development of Paroxysmal Nocturnal Haemoglobinuria (PNH) Market
B. Future Opportunities
10. Conclusion



Market Segmentation

By Treatment:

According to treatment market is segmented into medication, supplements, blood transfusion, bone marrow transplant and others.

By Drugs:

According to type of drug used market segments are Eculizumab, Ravulizumab and Others.

Alexion Pharmaceuticals’ Soliris (eculizumab) was the first drug approved for the treatment of patients with PNH by reducing haemolysis. The monoclonal antibody improves anaemia, decreases, or terminates the need for blood transfusions, and reduces clotting of blood. Alexion reports remarkable improvement in patients on Soliris, with a three-year survival rate of about 98.0% in the first five years of diagnosis.

By Mode of Administration:

The market segments based on mode of administration is oral and parenteral.

Top Players

The key market players in the paroxysmal nocturnal haemoglobinuria drug market are Alexion pharmaceuticals, Samsung Bioepis, Isu Abxis, F. Hoffmann-La Roche Ltd, Novartis, Amgen.

Research Methodology

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  1. Market overview
  2. Market growth drivers & restraints
  3. Epidemiology or disease type
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  5. Market share
  6. Competitive landscape
  7. Key company profiles
  8. Healthcare policies & regulatory framework
  9. Reimbursement scenario
  10. Factors driving future growth

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