South Korea Hereditary Angioedema (HAE) Therapeutics Market Analysis

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  • Type: Rare Disease Area
  • Published : June 2021
  • Region: Asia
  • Country: South Korea
  • Report ID : 4936

  • Format: PPT, PDF

South Korea Hereditary Angioedema (HAE) Therapeutics Market: Segmented By Drug Class (C1 Esterase Inhibitor, Selective Bradykinin B2 Receptor Antagonist, Kallikrein Inhibitor, and others) and By Route Of Administration (Intravenous, Subcutaneous, Oral) – Growth, Trends and Forecasts (2020 – 2028)

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Report Overview

The South Korea Hereditary Angioedema (HAE) Therapeutics market size stood at around USD xx billion in 2020 and is projected to reach xx billion by 2028, exhibiting a CAGR of around xx% during the forecast period.

Hereditary angioedema is a disease of congenital deficiency or functional defect in the C1 esterase inhibitor (C1-INH) consequent to mutation in the SERPING1 gene, which encodes C1-INH. This disease manifests as recurrent, non-pitting, non-pruritic subcutaneous, or submucosal oedema as well as an erythematous rash in some cases. These symptoms result from the uncontrolled localized production of bradykinin.

The most commonly affected sites are the extremities, face, gastrointestinal tract, and respiratory system. When the respiratory system is affected by hereditary angioedema, swelling of the airway can restrict breathing and lead to life-threatening obstruction. As per the National Organization for Rare Disorders (NORD), the prevalence of hereditary angioedema is 1 per 50,000 to 1 in 150,000 individuals worldwide. The expected number of patients in Korea is about 1,000. However, as of 2019, only 80 patients were diagnosed with hereditary angioedema in Korea.

Market Drivers

Growing cases of hereditary angioedema (HAE) and rising initiatives for improving awareness levels among the general population are factor contributing to the growth of the market. Pharmaceutical drug manufacturers are increasing focus on developing novel therapeutics for hereditary angioedema in order to cater to the large unmet medical needs. Government initiatives and increase in healthcare spending is also fuelling the HAE therapeutics market. For instance, Takeda Pharmaceutical Korea announced that the Ministry of Health and Welfare would grant expanded reimbursement for its acute hereditary angioedema seizure treatment, Firazyr, from March 2021. The ministry will expand the insurance benefits for Firazyr to two doses per patient from the existing one-dose regimen.

Significant number of patients are being misdiagnosed for the condition, also the number of undiagnosed cases it very high which impedes the market growth.

1. South Korea Hereditary Angioedema (HAE) Therapeutics Market Overview….
A. Market Size
2. Market Growth Drivers……………………………………………….
A. Demand For Innovative Drugs And Novel Technologies
B. Robust Drug Pipelines
C. Increase In Prevalence Of Non-Hodgkin’s Lymphoma
3. Types of Hereditary Angioedema (HAE)…………………………………………
A. Type I HAE
B. Type II HAE
C. Type III HAE
4. Hereditary Angioedema (HAE) Therapeutics Market Segmentation……
A. Drug Class
I. C1 Esterase Inhibitor
II. Selective Bradykinin B2 Receptor Antagonist
III. Kallikrein Inhibitor
IV. others
B. Route Of Administration
I. Intravenous
II. Subcutaneous
III. Oral
5. Hereditary Angioedema (HAE) Therapeutics Market Share…………………
A. Market Analysis, Insights and Forecast – By Revenue
6. Competitive Landscape………………………………………………
A. Major Players
B. Products in Pipeline
7. Key Company Profiles………………………………………………….
A. Takeda Pharmaceuticals Korea Company Overview, Product & Services, Strategies & Financials
B. Hyupjin Corporation Company Overview, Product & Services, Strategies & Financials
8. Healthcare Policies and Regulatory Landscape……………………………
A. Policy changes and Reimbursement scenario
9. Factors Driving Future Growth……………………………………
A. New Trends and Development of Hereditary Angioedema (HAE) Therapeutics Market
B. Future Opportunities
10. Conclusion

 

Market Segmentation

By Drug Class:

According to the drug class, market is segmented into C1 esterase inhibitor, selective bradykinin B2 receptor antagonist, kallikrein inhibitor, and others.

By Route of Administration:

According to route of administration, HAE therapeutics market segments are intravenous, subcutaneous and others.

 

Top Players

The hereditary angioedema therapeutics market is highly consolidated in terms of competition and consists of limited major players. Some of the companies which are currently dominating the market are Takeda Pharmaceutical Korea, Pharming Healthcare, BioCryst Pharmaceuticals, Sanofi.

Pharming Group N.V.  and their Seoul based South Korean specialty pharma partner Hyupjin have received the marketing authorization for Ruconest in South Korea since 2016. Ruconest was the first approved recombinant C1 esterase inhibitor worldwide.

Launch of Takeda Pharmaceutical Korea’s ‘Firazyr’ has improved the conditions of HAE patients in Korea tremendously. Firazyr is an emergency treatment used for the acute attack of hereditary angioedema over two years of age due to a deficiency of a C1-esterase inhibitor by blocking the vasodilating action of Bradykinin to relieve acute seizures within two hours.

Research Methodology

Insights10 will provide you reports within 10 key parameters which are:

  1. Market overview
  2. Market growth drivers & restraints
  3. Epidemiology or disease type
  4. Market segmentation
  5. Market share
  6. Competitive landscape
  7. Key company profiles
  8. Healthcare policies & regulatory framework
  9. Reimbursement scenario
  10. Factors driving future growth

Based on our many years of experience, we believe that these are the parameters that are critical to decision making for business stakeholders. Our focused approach to develop reports focused on 10 key parameters, enabled us to arrive at the name “Insights10”.

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The top-down approach mainly used for new product forecasting and bottom-up approach is used for demand estimation of any product for different countries summed up to form total market. We are able to round off insights and build stronger forecasts because we always do both these methods and triangulate the final numbers.

The study on the market covers the analysis of the leading geographies such as North America, Europe, Asia-Pacific, and Africa for the period of 2020 to 2028. The qualitative analysis covers the industry landscape and trends, market opportunities, competitive landscape and policy and regulatory scenario and the quantitative analysis covers different market estimates and forecasts.

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We make sure to finalize the numbers in alignment to the market research. Firstly, our internal experts ensure thorough validation and checking to ensure the accurate and precise analysis and then validation is also done using multiple data analysis model.  Two level validation is done and entails finalization of report scope and to way of representation pattern.

Stage III: Interpretation and Presentation

Analysis & Interpretation: The information gathered is then analysed and synthesized. A second series of interviews are done if necessary to check and validate. The future opportunities are analysed by understanding product commercialization and many other factors. It also comprises the analysis of data discrepancies observed across various data sources. Information procured from secondary and primary results are then, interpreted by considering following parameters: (a partial list)

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Data curated from the analysis and interpretation are drawn to portray all in one consolidated report.

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The foreign exchange rates are calculated on the respective dates and for the respective regions covered in the study.

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