Global Spinal Muscular Atrophy (SMA) Treatment Market

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  • Type: Rare Disease Area
  • Published : March 2021
  • Region: Worldwide
  • Country: Other
  • Report ID : 365

  • Format: PPT, PDF

Global Spinal Muscular Atrophy (SMA) Treatment Market Sizwe, Share and Industry Analysis, by Product, by Distribution Channel and  Region Forecast 2019-2028

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Market Overview

The Global Spinal Muscular Atrophy Treatment market size stood at around USD 1.82 billion in 2019 and is projected to reach USD xx billion by 2028, exhibiting a CAGR of xx% during the forecast period 2019-2028

The global market growth is driven by a significant increase in the number of product launches despite the relative rarity of the disorder and high costs associated with the approved drugs. The treatment of spinal muscular atrophy through the gene therapy drug called Zolgensma by the Swiss drugmaker Novartis comes with a price tag of USD 2.1 million, for a one-time treatment. Despite such high costs, the severity of the disorder, which is considered the leading genetic cause of death in infants, is driving the adoption of these expensive drugs

Market Growth Drivers

The overall burden of spinal muscular atrophy is one of the highest in terms of cost and healthcare services in the rare disorder. The rising incidence of spinal muscular atrophy due to the increasing population is one of the key factor for the growth in global SMA treatment market. The increasing incidence and awareness for spinal muscular atrophy have increased remarkably which is propelling the demand for efficient therapeutic options leading to better patient outcomes. In recent times, there have been two substantial and very significant product launches in gene therapy for the treatment of spinal muscular atrophy

Spinal Muscular Atrophy Treatment Market  by Disease Type

The spinal muscular atrophy treatment market has been segmented on the basis of major disease type which are Type 1 SMA, Type 2 SMA and others. Type 1 SMA generated the highest revenue amongst the three categories in 2018 and is expected to remain dominant in terms of revenue throughout the forecast duration. Type 1 SMA is anticipated to remain the most dominant because the majority of the cases of the disorder are of this type, which has led to it dominating in terms of market share. Increasing awareness of the Type 2 SMA and increasing adoption of treatment is also anticipated to drive the growth of this type in the forecast period

1. Global Spinal Muscular Atrophy (SMA) Treatment Market Overview………….
A. Market Size
2. Market Growth Drivers……………….…………………………………..……………….
A. Growing incidence of Spinal Muscular Atrophy
B. New Product Launches with High Awareness
3. Spinal Muscular Atrophy by Disease Type………………………………………
A. Type 1 SMA
B. Type 2 SMA
C. Others
4. Global Spinal Muscular Atrophy Treatment Market Segmentation………………
A. By Product
I. Nusinersen
II. Onasemnogen Abeparvovec
B. By Distribution Channel
I. Hospital Pharmacy
II. Retail Pharmacy
III. Others
C. By Geography
I. North America Market Analysis
II. Asia-Pacific Market Analysis
III. Europe Market Analysis
IV. South America Market Analysis
V. Middle-East and Africa Market Analysis
5. Spinal Muscular Atrophy Treatment Major Market Share……………….……………..
A. Market Analysis, Insights and Forecast by Revenue
6. Competitive Landscape………………………………………………………….………..
A. Major Players
B. Products in Pipeline
7. Key Company Profiles…………………………………………………………………….
A. Biogen Company overview, Product & Services, Strategies & Financials
B. Novartis Company overview, Product & Services, Strategies & Financials
C. Genentech Company overview, Product & Services, Strategies & Financials
8. Healthcare Policies and Regulatory Landscape….…………………………………..
A. Policy Changes and Reimbursement Scenario
9. Factors Driving Market Growth………………………………………………………….
A. Key Industry Developments
10. Conclusion

Market Segmentation

By Product:

Based on product, the market is segmented into Nusinersen and Onasemnogen Abeparvovec. Nusinersen accounted for maximum share in 2018, which is attributable to the fact that in 2018, Nusinersen was the only approved product available in the market. However, Onasemnogen Abeparvovec who gained approval in 2019, is anticipated to be launched in several markets over the periods of 2019 and 2020. Onasemnogen Abeparvovec is expected to witness growth in the coming years owing to the rising launches in the number of markets across the globe and greater patient adoption

By Distribution Channel:

By distribution channel, the global SMA treatment market is categorized into hospital pharmacies, retail pharmacies, and others. In terms of value, hospital pharmacies accounted for the leading market share in 2018, which is attributable to the fact that the majority of the medications for treatment can be only administered intravenously and can so only be done by trained medical professionals. Hence, the retail pharmacies segment registers a comparatively lower CAGR

By Region:

SMA treatment market in North America was valued at USD 854.0 million in 2018. Early approvals for SMA treatment products in the U.S., coupled with adequate reimbursement, has led to growing number of patients being treated in 2018.

Europe is expected to hold the second leading position in this market by witnessing strong growth in long-term period. As per our market research study, Asia Pacific is expected to witness relatively significant growth in terms of spinal muscular atrophy treatment market value. Funding by public and private players to improve the accessibility of high-cost treatment options is likely to augment the expansion of the market during the forecast period. For instance, in the key regions of Asia such as Japan and Hong Kong have granted the status of reimbursed access to all patients, while in China, the process of reimbursement approval is currently underway. Such a positive reimbursement scenario for spinal muscular atrophy treatment is projected to boost the expansion of the market in Asia-Pacific during the forecast period.

The rest of the world comprises of the regions of Latin America and Middle East & Africa. In Latin America, the rising incidence of the disorder among the population is boosting the spinal muscular atrophy treatment market growth. Middle East & Africa is estimated to reflect slower-to-moderate growth during the forecast period, which is attributable to the delayed diagnosis of the disorder in African countries. However, positive reimbursement policies in the region in the countries in Middle East and growing awareness for the severity of the disease are the key factors estimated to propel the revenue from Middle East & Africa spinal muscular atrophy (SMA) treatment market during the forecast period

Top Major Players

Biogen and Novartis AG accounted for the complete market share in 2018, owing to their two main products for the treatment of spinal muscular atrophy. Spinraza (Nusinersen) by Biogen and Zolgensma (Onasemnogene abeparvovec) by Novartis are the only two products approved for the treatment of this disorder. Hence, these two companies hold complete dominance in terms of the market share. The other companies such as Genentech, Inc. (F. Homann-La Roche Ltd) and Astellas Pharma hold key pipeline candidates, some of which are in the advanced stages of clinical trials.

Research Methodology

Insights10 will provide you reports within 10 key parameters which are:

  1. Market overview
  2. Market growth drivers & restraints
  3. Epidemiology or disease type
  4. Market segmentation
  5. Market share
  6. Competitive landscape
  7. Key company profiles
  8. Healthcare policies & regulatory framework
  9. Reimbursement scenario
  10. Factors driving future growth

Based on our many years of experience, we believe that these are the parameters that are critical to decision making for business stakeholders. Our focused approach to develop reports focused on 10 key parameters, enabled us to arrive at the name “Insights10”.

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The top-down approach mainly used for new product forecasting and bottom-up approach is used for demand estimation of any product for different countries summed up to form total market. We are able to round off insights and build stronger forecasts because we always do both these methods and triangulate the final numbers.

The study on the market covers the analysis of the leading geographies such as North America, Europe, Asia-Pacific, and Africa for the period of 2020 to 2028. The qualitative analysis covers the industry landscape and trends, market opportunities, competitive landscape and policy and regulatory scenario and the quantitative analysis covers different market estimates and forecasts.

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We make sure to finalize the numbers in alignment to the market research. Firstly, our internal experts ensure thorough validation and checking to ensure the accurate and precise analysis and then validation is also done using multiple data analysis model.  Two level validation is done and entails finalization of report scope and to way of representation pattern.

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The foreign exchange rates are calculated on the respective dates and for the respective regions covered in the study.

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