Global Gram-Negative Infection Therapeutic Market

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  • Type: Common Disease Area
  • Published : March 2021
  • Region: Worldwide
  • Country: Other
  • Report ID : 207

  • Format: PPT, PDF

Global Gram-Negative Infection Therapeutics Market: Segmented by Infections, by Treatment (Carbapenems, Colistin, Tigecycline, Sulbactam, Doxycycline, and Rifampin) by Product Type (Enteral, Parenteral, others), End-User Application & Geography (North America, Europe, Asia-Pacific, Middle-East and Africa, and South America) – Growth, Trends, and Forecasts (2019 – 2028)

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Report Overview

The global marketplace for Gram-negative bacteria was valued 2.43 Billion in 2019 and is projected to exceed $xx billion by 2028, at a Compound Annual Growth Rate (CAGR) of 10.8% from 2019–2028.

According to the list made public by the WHO, among the various MDR Gram-negative bacterial organisms, few that pose significant remerging threats and are of high priority include Pseudomonas aeruginosa, Acinetobacter Baumann, Enterobacteriaceae, Enterococcus faecium, Helicobacter pylori, Helicobacter pylori, Neisseria gonorrhoeae. Most of these are associated with causing urinary tract infections, nosocomial infections, and pneumonia. The mounting burden of these infections on public health, especially in emerging nations, is attributed to the rate of antibiotic resistance growing at a faster pace than the pace at which new drugs are being developed Hence, it becomes all the more mandatory that pharmaceutical companies and drug makers to actively focus on expanding the armory of novel therapeutics and accelerate clinical researches in the coming years

Market Growth Drivers

The rising prevalence of various rare diseases globally is expected to support the criteria of the hospital-treated gram-negative infections market. There has been a rising need for newer drugs for getting the appropriate effect on the micro-organisms. The increasing number of strains of the bacteria and growing resistance towards the previously existing pathogens are expected to favor the market for drugs used in hospital-treated gram-negative infections. The world is running out of drugs for infections caused due to gram-negative bacteria. However, companies are laying efforts in drug discoveries by spending more and more on research and development. Furthermore, among all of the bacterial resistance problems, gram-negative pathogens are particularly troublesome and a reason for a major worry in the physician community as they are getting resistant to the maximum currently available drugs. The most common gram-negative infections include the pathogens such as Enterobacteriaceae, Pseudomonas aeruginosa, and Acinetobacter. Major challenges are rising for the treatment of patient suffering from pan-resistant or nearly pan-resistant gram-negative microorganisms

1. Global Gram-Negative Market Overview………………………………………………………..
A. Market Size
2. Market Growth Drivers……………………………………………………………………………………….
A. Rising need for newer drugs for getting the appropriate effect on the micro-organisms.
B. Increasing number of strains of the bacteria and growing resistance
C. Rising prevalence of various rare disease
3. Epidemiology and Disease Management of Gram-Negative infection
A. Prevalence of Gram-negative infection cases
B. Incidence of Gram-negative infection cases
4. Gram-Negative Market Segmentation…………………………………………………………….
A. By Therapy
I. Cephalosporin, Aminoglycoside
II. Ampicillin/sulbactam, Carbapenem, Colistin or Rifampin
III. Aminoglycoside, Carbapenem, Colistin, Fosfomycin, Rifampin, or Tigecycline
IV. Ceftolozane/Tazobactam
V. Ceftazidime/Avibactam
VI. Others
B. By Geography
I. North America Market Analysis
II. Europe Market Analysis
III. Asia-Pacific Market Analysis
IV. Middle-East and Africa Market Analysis
V. South America Market Analysis
5. Gram-Negative Product Market Share……………………………………………………
A. Market Analysis, Insights and Forecast – By Revenue
6. Competitive Landscape………………………………………………………………………………
A. Major Players
B. Products in Pipeline
7. Key Company Profiles………………………………………………………………………………….
A. Merck Company overview, Product & Services, Strategies & Financials
B. Pfizer Company overview, Product & Services, Strategies & Financials
C. AstraZeneca Company, Product & Services, Strategies & Financials
8. Healthcare Policies and Regulatory Landscape……………………………………..
A. Policy changes and Reimbursement scenario
9. Factors Driving Future Growth………………………………………………………………….
A. New Trends and Development of Gram-Negative Bacterial Infection market
B. Future Opportunities
10. Conclusion

Market Segmentation

By Treatment:

In terms of treatment, the global gram-negative bacterial infection market can be divided into Carbapenems, Colistin, Tigecycline, Sulbactam, Doxycycline, and Rifampin. The demand for carbapenes is high for the treatment of gram-negative bacterial infections, particularly pneumonia. Some of the most commonly used carbapenes for the treatment of pneumonia are meropenem, imipenem, and doripenem. Sulbactam is majorly used for the treatment of meningitis. However, colistin, tigecycline, doxycycline, and rifampin are used for treating every type of gram-negative bacterial infection and are, therefore, likely to be adopted more in the long run

By Infection:

On the basis of type of infection, the global gram-negative bacterial infection market can be segmented into wound or surgical site infections, pneumonia, urinary tract infections, bloodstream infections, and meningitis. Pneumonia is the most common disease caused by gram-negative bacteria followed by urinary tract infections. According to a report by the World Health Organization (WHO), this disease killed 920 136 children under the age of 5 in 2015. Meningitis is also a common disease caused by these organisms. A study conducted by one of the key players in the market, Merck & Co. Inc., indicates that about 25% of the newborns who suffer from gram-negative bacteria-induced meningitis die, and 15% to 20% of the infants develop serious brain and nerve problems such as enlargement of ventricles, deafness, cerebral palsy, and mental retardation. The alarming rate of mortality and morbidity due to these organisms is escalating the growth of the market

By Region:

On the basis of region presence, the hospital-treated gram-negative infections market is segmented into five key regions: North America, Latin America, Europe, Asia-Pacific, and Middle East & Africa. Presently, North America dominates the global market for hospital-treated gram-negative infections due to the existing large number of facilities for research and development. However, growth in the Asia-Pacific region is significant in terms of CAGR over the forecast period due to rising in resistance due to improper scheduled of antibiotics administration. The U.S. Hospital-treated gram-negative infections market is expected to dominate in terms of market share with a significant share among all the regions

Top 5 Major Players

Many new players are emerging in the dermatological therapeutics market, as a result of a number of growth opportunities. Forthcoming patent expiries of major drugs are leading to increased competition, and it is further driving the market studied, especially in the generic sector. The overall dermatological diagnostics and therapeutics industry is expected to witness tremendous growth, with several generic players controlling significant market share in the developing regions. Some of the companies which are currently dominating the market are Amgen Inc., Bausch Health Companies Inc., Novartis International AG, AbbVie Inc., and Allergan PLC

 

 

Research Methodology

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  1. Market overview
  2. Market growth drivers & restraints
  3. Epidemiology or disease type
  4. Market segmentation
  5. Market share
  6. Competitive landscape
  7. Key company profiles
  8. Healthcare policies & regulatory framework
  9. Reimbursement scenario
  10. Factors driving future growth

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The study on the market covers the analysis of the leading geographies such as North America, Europe, Asia-Pacific, and Africa for the period of 2020 to 2028. The qualitative analysis covers the industry landscape and trends, market opportunities, competitive landscape and policy and regulatory scenario and the quantitative analysis covers different market estimates and forecasts.

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