Global Car T-Cell Therapy Market Analysis

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  • Type: Oncology area
  • Published : March 2021
  • Region: Worldwide
  • Country: Other
  • Report ID : 244

  • Format: PPT, PDF

Global CAR T-Cell Therapy Market Segmented by Target Antigen (CD19, CD22 and Others), and by Region (North America, Europe, Latin America and Rest of the World) – Growth, Trends and Forecast, 2019-2028

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Report Overview

The global CAR T-Cell therapy market size stood at around USD 482.2 million in 2019 and is projected to reach USD xx million by 2028, exhibiting a CAGR of xx% during the forecast period.

In the recent years, cancer has become one the major cause of deaths worldwide and companies are coming up with various conventional and cytotoxic immunotherapies in the market. Keeping into consideration the complex behaviour of tumours and the involvement of varied genetic and cellular factors in tumorigenesis and metastasis, companies are focusing on developing new treatments which would focus on targeting tumours at both genetic and cellular level.

Chimeric Antigen Receptor (CAR) T cell therapy is one such novel therapeutic treatment which comprises reengineering cancer patient’s white blood cells (WBC) to fight the malignant cells by recognizing them. During this therapy, the person’s T cells are extracted, preciously reformed and then inserted again to the person’s body where the restructured cell multiply and target cancer cells.

Market Drivers and Restraints

Growing prevalence of cancer across the world, technological advancement for advanced & reliable treatment for cancer, and rise in the number of cell therapy clinical studies are driving the growth of the global CAR T cell therapy market. Drastic rise in CAR T-Cell trials also acts as a driver for the market growth.

However, side effects and high cost of treatment of CAR T-Cell therapy are key restraints for the market growth.

Major CAR T-Cell Therapy Market by Disease Indication

The major disease includes Diffuse Large B-Cell Lymphoma (DLBCL), Acute Lymphoblastic Leukemia (ALL), Chronic Lymphocytic Leukemia (CLL), Multiple Myeloma (MM), Follicular Lymphoma and Others.

It is estimated that the market for DLBCL has the highest market share and is estimated to grow at a CAGR of 22.9% during the forecast period. The market for Multiple myeloma is also expected to grow at a faster pace reaching approximately USD 4.2 billion by 2028. The first therapy approved was in paediatrics and/or young adults Acute Lymphoblastic leukaemia (ALL), an ailment with a high unmet need where CAR-T indicated high effectiveness, nonetheless, which represents a very small patient population.

1. Global CAR T-Cell Therapy Market Overview…………………………………………..
A. Market Size
2. Market Growth Drivers and Restraints…………………………………..……………….
A. Market Drivers
I. Rising Number of Patients with Hematologic Cancers
II. Dramatic Rise in Global CAR T-Cell Trials
B. Market Restraints
I. High Treatment Cost of CAR T-Cell Therapy
II. Side Effects of CAR T-Cell Therapy
3. Major CAR T-Cell Therapy Market by Disease Indication…..…………….………….
A. Diffuse Large B-Cell Lymphoma (DLBCL)
B. Acute Lymphoblastic Leukemia (ALL)
C. Chronic Lymphocytic Leukemia (CLL)
D. Multiple Myeloma (MM)
E. Follicular Lymphoma
F. Others
4. CAR T-Cell Therapy Market Segmentation………………………..…………………….
A. By Target Antigen
I. CD19
II. CD22
III. Others
B. By Region
I. North America Market Analysis
II. Europe Market Analysis
III. Asia-Pacific Market Analysis
IV. South America Market Analysis
V. ROW (Rest-of-the-world) Market Analysis
5. CAR T-Cell Therapy Major Market Share………………………………..
A. Market Analysis, Insights and Forecast
6. Competitive Landscape………………………………………………………….………..
A. Major Players
B. Mergers and Acquisition
7. Key Company Profiles…………………………………………………………………….
A. Novartis Company overview, Product & Services, Strategies & Financials
B. Pfizer Company overview, Product & Services, Strategies & Financials
C. Kite Pharma Company overview, Product & Services, Strategies & Financials
8. Factors Driving Future Growth…………………………………………………………..
A. Key Industry Developments
9. Market Opportunities……………………………….….…………………………………..
A. Investigation On CAR-T Therapy For The Treatment Of Several Hematologic And Solid Tumour Types
10. Conclusion

Market Segmentation

By Targeted Antigen:

On the basis of targeted antigen, the market of CAR T-Cell therapy market is segmented into CD19, CD22 and others.

By Region:

By geography, the neurologic disorders therapeutics market is divided into North America, Asia Pacific, South America, Europe and ROW (Rest of the World). In terms of market size, North America is dominant in the global CAR-T cell therapy market. This is attributed to rapid development and launch of new therapies for the treatment of cancer by key players in the market in the region. Asia Pacific is expected to exhibit highest growth over the forecast period, owing to increasing number of global players collaborating and signing research as well as manufacturing contracts for CAR-T cell therapies with local players in the region.

Top Major Players

The prominent players in the global CAR T cell therapy market are Novartis AG (Switzerland), Pfizer, Inc. (US), Kite Pharma (US), Cellectis (France), Autolus Therapeutics PLC (UK), CARsgen Therapeutics (China), Juno Therapeutics (US), Sorrento Therapeutics (US), Legend Biotech (US), Mustang Bio (US), and others.

Research Methodology

Insights10 will provide you reports within 10 key parameters which are:

  1. Market overview
  2. Market growth drivers & restraints
  3. Epidemiology or disease type
  4. Market segmentation
  5. Market share
  6. Competitive landscape
  7. Key company profiles
  8. Healthcare policies & regulatory framework
  9. Reimbursement scenario
  10. Factors driving future growth

Based on our many years of experience, we believe that these are the parameters that are critical to decision making for business stakeholders. Our focused approach to develop reports focused on 10 key parameters, enabled us to arrive at the name “Insights10”.

Our analysis methodology involves three critical stages:

Stage I: Market Data Collection

Primary Interviews: We have developed a network of experts, freelancers and researchers across countries through which we engage with local experts to gather key data points and assumptions around each market. We also engage regularly with some of the best market research agencies such as Atheneum, GuidePoint, GLG, etc. to conduct surveys and interviews, and build intelligence. We have language translators as a part of our team, who between them can cover 30+ languages allowing us to extract better local insights.

Secondary Data Collection: We have developed strong expertise and experience in secondary data collection methods for developing unique data sets and research material. We gather data from multiple reliable sources to maintain the high level of accuracy and consistency. The market data is analysed and forecasted using appropriate statistical and coherent models. The report offers an overall analysis of the market size, growth, market share as well as segment-level analysis of the specific market. Our report includes precise, to the point information related to the overall market, competition, growth drivers, challenges, regulatory updates, and competition.

Data Sources: We have access to multiple highly reliable free and subscription data sources. We have many years of experience to understand which sources are more dependable for what and which to prefer for the reliable and latest information. The key sources of information include the following, but are not limited to:

  • Statistical Databases
  • Company Websites/Annual Reports
  • Trade Publications
  • Online Databases
  • Published Research Reports
  • Whitepapers
  • Press Releases of Key Market Players

Stage II: Market Data Analysis and Statistical Model

Market Trends: We generally look at macro parameter and micro indicators. The macro parameters includes changes in government policies, demand and supply of the market, government intervention programs and major market share. The micro indicators GDP growth, market size, market volume etc. We also understand nuances specific to each country like US, Canada, India, Germany, etc. and have worked across 60+ countries and hence no only understand global trends, but how these differ by country, how payment models, market structure, cultural parameters, etc. differ in each country.

Market Sizing and Analysis: Our expert data analytics team has created various market forecast models by employing the top-down approach i.e. start with large overall market and segment different areas and bottom-up approach i.e. start with population and epidemiology and roll up based on spend, etc., estimating the size of the market, and distributing among the geographic and/or product segments.

The top-down approach mainly used for new product forecasting and bottom-up approach is used for demand estimation of any product for different countries summed up to form total market. We are able to round off insights and build stronger forecasts because we always do both these methods and triangulate the final numbers.

The study on the market covers the analysis of the leading geographies such as North America, Europe, Asia-Pacific, and Africa for the period of 2020 to 2028. The qualitative analysis covers the industry landscape and trends, market opportunities, competitive landscape and policy and regulatory scenario and the quantitative analysis covers different market estimates and forecasts.

Data Triangulation & Validation:

Data triangulation of various sources and results of the research are carried out by benchmarking with reliable sources such as industry statistics, statistical databases and the company level averages etc.

We make sure to finalize the numbers in alignment to the market research. Firstly, our internal experts ensure thorough validation and checking to ensure the accurate and precise analysis and then validation is also done using multiple data analysis model.  Two level validation is done and entails finalization of report scope and to way of representation pattern.

Stage III: Interpretation and Presentation

Analysis & Interpretation: The information gathered is then analysed and synthesized. A second series of interviews are done if necessary to check and validate. The future opportunities are analysed by understanding product commercialization and many other factors. It also comprises the analysis of data discrepancies observed across various data sources. Information procured from secondary and primary results are then, interpreted by considering following parameters: (a partial list)

  • Establishing market drivers and trends
  • Analyzing regulatory landscape to understand future growth
  • Market Segment based analysis to obtain revenue / volume
  • Analyzing current needs and determining penetration to estimate market

Insights: Our reports deliver actionable insights backed with supporting facts and figures to assist you in achieving exemplary growth. Our in-depth analyses are interspersed with relevant insights and statistics to offer an executive-level view of a given market. The description helps in correlating many minor factors affecting the market and its impact to the different segments within the market.
Data curated from the analysis and interpretation are drawn to portray all in one consolidated report.

Presentation & Reporting: The market research report is presented in different forms such as charts by using a scientific approach for easy understanding. Historic, current and future analysis is provided for each market in terms of both value and volume. The size of the market is interpreted in the US Dollar value and the respective unit, based on the product, for volume consumptions.
The foreign exchange rates are calculated on the respective dates and for the respective regions covered in the study.

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