Global Alport Sydrome Market Analysis

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  • Type: Rare Disease Area
  • Published : March 2021
  • Region: Worldwide
  • Country: Other
  • Report ID : 402

  • Format: PPT, PDF

Global Alport Syndrome Market Segmented by Diagnosis (Kidney Biopsy, Skin Biopsy, Genetic Testing), by End Users (Hospitals, Diagnostic Centers & Laboratories), by Geography (North America, Europe, Asia-Pacific, South America and Middle East and Africa) and by Disease type (X-linked Alport Syndrome, ARAS & ADAS) – Growth, Trends and Forecast, 2019-2028

 

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Report Overview

The global Alport Syndrome market size stood at around USD 0.33 billion in 2019 and is projected to reach USD xx billion by 2028, exhibiting a CAGR of xx% during the forecast period

Alport syndrome is a rare genetic condition characterized by kidney disease, hearing loss, and eye abnormalities. This condition is caused by mutation in the genes COL4A3, COL4A4, and COL4A5, which are involved in the production of proteins such as type IV collagen. Patients suffering from Alport syndrome suffer from progressive loss of kidney function. Presence of blood in urine indicates abnormal functioning of the kidneys. A number of patients suffering from Alport syndrome develop high levels of proteins in the urine. As the condition progresses, the kidney function deteriorates leading to end-stage renal disease (ESRD)

 

Market Drivers and restraints 

Rise in prevalence of genetic disorders is likely to augment the global Alport syndrome market. There is no cure for this syndrome. Hence, availability of drugs for the management of its symptoms such as high blood pressure is projected to boost the growth of the global market. Demand for genetic testing as an effective diagnostic procedure for Alport syndrome is anticipated to drive the global Alport syndrome market. Moreover, skin biopsy and kidney biopsy are used for diagnosis of the early symptoms of Alport syndrome and faster adoption of these diagnostic techniques is a major factor propelling the global market. High investments by the key players and initiatives by governments for research and development of drugs for managing Alport syndrome and its symptoms are likely to propel the global Alport syndrome market. Hence, faster adoption and availability of diagnostic tests across the globe are anticipated to augment the global Alport syndrome market. However, low awareness about the syndrome and its lower diagnosis rates in underdeveloped countries act as major restraints of the global Alport syndrome market

1. Global Alport Syndrome Treatment Market Overview…
A. Market Size
2. Global Alport Syndrome Treatment Market Growth Drivers
A. Rise in prevalence of genetic disorder
B. Rising investments and initiatives by government
C. Availability of diagnostic tests and demand for genetic testing
3. Global Alport Syndrome Treatment Market Segmentation
A. By Diagnosis
I. Kidney Biopsy
II. Skin Biopsy
III. Genetic Testing
B. By Region
I. North America Market Analysis
II. Europe Market Analysis
III. Asia-Pacific Market Analysis
IV. South America Market Analysis
V. Middle East and Africa Market Analysis
C. By End User
I. Hospitals
II. Diagnostic Centres & Laboratories
D. By Disease type
I. X-linked Alport Syndrome
II. Autosomal Recessive Alport Syndrome
III. Autosomal Dominant Alport Syndrome
4. Global Alport Syndrome Treatment Major Market Share
A. Market Analysis, Insights and Forecast by revenue
5. Competitive Landscape……………………………………
A. Major Players
B. Products in Pipeline
6. Key Company Profiles……………………………………
A. Mylan N.V Company overview, Product & Services, Strategies & Financials
B. Novartis Company overview, Product & Services, Strategies & Financials
C. Baxter  Company overview, Product & Services, Strategies & Financials
7. Healthcare Policies and Regulatory Landscape….…………
A. Policy Changes and Reimbursement Scenario
8. Factors Driving Market Growth………………………………..
A. Key Industry Developments
B. Mergers and Acquisitions
9. Market Opportunities and Future Trends…………………
A. Market Opportunities
B. Future Trends
10. Conclusion

Market Segmentation

By Diagnosis type

Diagnostics are divided into three types Kidney Biopsy, Skin Biopsy, Genetic testing. Mostly, kidney biopsy is the preferred approach because it is less invasive compared with other approaches. Other kidney biopsy methods include open (surgical) biopsy

By End User

On the basis of end user, the market is segmented into hospitals , diagnostics clinics & laboratories

By Disease Type

Alport Syndrome has disease types such as X-linked Alport Syndrome (XLAS), Autosomal Recessive Alport Syndrome (ARAS), Autosomal Dominant Alport Syndrome (ADAS)

X-linked Alport syndrome (XLAS) is the most common. In these families, affected males typically have more severe disease than affected females. In autosomal recessive Alport syndrome (ARAS) the severity of disease in affected males and females is similar

By Region

On the basis Alport Syndrome the segmented countries are North America, Europe, Asia Pacific and South America

North America dominated the global Alport syndrome market owing to the increase in incidence of the condition, advanced health care system, and presence of diagnostics companies. Additionally, advanced diagnostic tests and broad network of laboratories are anticipated to fuel the growth of the Alport syndrome market in North America. According to the Alport Syndrome Foundation, Alport syndrome affected around 200,000 people in the U.S. in 2017. Moreover, the syndrome is estimated to affect around 1 in 5,000 to 10,000 people in the country, which is 30,000 to 60,000 people. Moreover, Alport syndrome is estimated to affect around 3% of children with chronic kidney disease (CKD) and 0.2% of adults with end stage renal disease (ESRD)

Europe was the second largest market for Alport syndrome diagnostics in 2018, followed by Asia Pacific. Clinical trials by key players and availability of advanced diagnostic tests for Alport syndrome are likely to augment the Alport syndrome market in Europe. Approval of Bardoxolone methyl by the EMA in May 2018 for chronic kidney disease, a symptom of Alport syndrome substantiates the fast track approval in Europe. Asia Pacific is projected to be the fastest growing market for Alport syndrome diagnostics

Top Major Players 

The major players covered in the Alport syndrome market are Mylan N.V., Novartis AG, Hikma Pharmaceuticals PLC, Sun Pharmaceuticals Industries Ltd., Wockhardt, Baxter, Ipca Laboratories Ltd., Emcure, Amneal Pharmaceutical LLC among other domestic and global players

Research Methodology

Insights10 will provide you reports within 10 key parameters which are:

  1. Market overview
  2. Market growth drivers & restraints
  3. Epidemiology or disease type
  4. Market segmentation
  5. Market share
  6. Competitive landscape
  7. Key company profiles
  8. Healthcare policies & regulatory framework
  9. Reimbursement scenario
  10. Factors driving future growth

Based on our many years of experience, we believe that these are the parameters that are critical to decision making for business stakeholders. Our focused approach to develop reports focused on 10 key parameters, enabled us to arrive at the name “Insights10”.

Our analysis methodology involves three critical stages:

Stage I: Market Data Collection

Primary Interviews: We have developed a network of experts, freelancers and researchers across countries through which we engage with local experts to gather key data points and assumptions around each market. We also engage regularly with some of the best market research agencies such as Atheneum, GuidePoint, GLG, etc. to conduct surveys and interviews, and build intelligence. We have language translators as a part of our team, who between them can cover 30+ languages allowing us to extract better local insights.

Secondary Data Collection: We have developed strong expertise and experience in secondary data collection methods for developing unique data sets and research material. We gather data from multiple reliable sources to maintain the high level of accuracy and consistency. The market data is analysed and forecasted using appropriate statistical and coherent models. The report offers an overall analysis of the market size, growth, market share as well as segment-level analysis of the specific market. Our report includes precise, to the point information related to the overall market, competition, growth drivers, challenges, regulatory updates, and competition.

Data Sources: We have access to multiple highly reliable free and subscription data sources. We have many years of experience to understand which sources are more dependable for what and which to prefer for the reliable and latest information. The key sources of information include the following, but are not limited to:

  • Statistical Databases
  • Company Websites/Annual Reports
  • Trade Publications
  • Online Databases
  • Published Research Reports
  • Whitepapers
  • Press Releases of Key Market Players

Stage II: Market Data Analysis and Statistical Model

Market Trends: We generally look at macro parameter and micro indicators. The macro parameters includes changes in government policies, demand and supply of the market, government intervention programs and major market share. The micro indicators GDP growth, market size, market volume etc. We also understand nuances specific to each country like US, Canada, India, Germany, etc. and have worked across 60+ countries and hence no only understand global trends, but how these differ by country, how payment models, market structure, cultural parameters, etc. differ in each country.

Market Sizing and Analysis: Our expert data analytics team has created various market forecast models by employing the top-down approach i.e. start with large overall market and segment different areas and bottom-up approach i.e. start with population and epidemiology and roll up based on spend, etc., estimating the size of the market, and distributing among the geographic and/or product segments.

The top-down approach mainly used for new product forecasting and bottom-up approach is used for demand estimation of any product for different countries summed up to form total market. We are able to round off insights and build stronger forecasts because we always do both these methods and triangulate the final numbers.

The study on the market covers the analysis of the leading geographies such as North America, Europe, Asia-Pacific, and Africa for the period of 2020 to 2028. The qualitative analysis covers the industry landscape and trends, market opportunities, competitive landscape and policy and regulatory scenario and the quantitative analysis covers different market estimates and forecasts.

Data Triangulation & Validation:

Data triangulation of various sources and results of the research are carried out by benchmarking with reliable sources such as industry statistics, statistical databases and the company level averages etc.

We make sure to finalize the numbers in alignment to the market research. Firstly, our internal experts ensure thorough validation and checking to ensure the accurate and precise analysis and then validation is also done using multiple data analysis model.  Two level validation is done and entails finalization of report scope and to way of representation pattern.

Stage III: Interpretation and Presentation

Analysis & Interpretation: The information gathered is then analysed and synthesized. A second series of interviews are done if necessary to check and validate. The future opportunities are analysed by understanding product commercialization and many other factors. It also comprises the analysis of data discrepancies observed across various data sources. Information procured from secondary and primary results are then, interpreted by considering following parameters: (a partial list)

  • Establishing market drivers and trends
  • Analyzing regulatory landscape to understand future growth
  • Market Segment based analysis to obtain revenue / volume
  • Analyzing current needs and determining penetration to estimate market

Insights: Our reports deliver actionable insights backed with supporting facts and figures to assist you in achieving exemplary growth. Our in-depth analyses are interspersed with relevant insights and statistics to offer an executive-level view of a given market. The description helps in correlating many minor factors affecting the market and its impact to the different segments within the market.
Data curated from the analysis and interpretation are drawn to portray all in one consolidated report.

Presentation & Reporting: The market research report is presented in different forms such as charts by using a scientific approach for easy understanding. Historic, current and future analysis is provided for each market in terms of both value and volume. The size of the market is interpreted in the US Dollar value and the respective unit, based on the product, for volume consumptions.
The foreign exchange rates are calculated on the respective dates and for the respective regions covered in the study.

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