China Spinal Muscular Atrophy (SMA) Therapeutics Market


  • Type: Rare Disease Area
  • Published : April 2021
  • Region: Asia
  • Country: China
  • Report ID : 1613

  • Format: PPT, PDF

China Spinal Muscular Atrophy (SMA) Therapeutics Market: Segmented by Therapy (Gene Replacement Therapy, Physical Therapy and Occupational Therapy), Route of Administration (Oral and Intrathecal)- Size, Share, Growth, Trends, and Forecasts (2020 – 2028)

SKU: 1613 Categories: ,

Report Overview

China Spinal Muscular Atrophy (SMA) Therapeutics market size stood at around USD xx billion in 2020 and is projected to reach USD xx billion by 2028, exhibiting a CAGR of 11.7% during the forecast period.

Spinal muscular atrophy (SMA) is a group of inherited disorders characterized by a loss of certain nerve cells in the spinal cord called motor neurons or anterior horn cells. The loss of motor neurons leads to progressive muscle weakness and muscle wasting (atrophy) in muscles closest to the trunk of the body (proximal muscles) such as the shoulders, hips and back. SMA affects between 1 in 6,000 and 1 in 10,000 in China, and about 95 percent of the patients die 18 months after birth. SMA type 1 is the most common type of SMA and is also a severe form of the disease.

Market Drivers

China is a growing market for spinal muscular atrophy (SMA) due to factors such as increase in China’s incidence rate (1 in 6,000 and 1 in 10,000). In addition to this, other factors that contribute to the growth of market are rise in healthcare expenditure, increase in awareness and availability of novel therapeutics and unmet needs of patients.

However, there are some restraining factors for growth of spinal muscular atrophy (SMA) therapeutics market in China such high cost of treatment for spinal muscular atrophy (SMA) and lack of experienced professionals.

1. China Spinal Muscular Atrophy (SMA) Therapeutics Market Overview……..
A. Market Size
2. Market Growth Drivers………………………………………………………………………
A. Increase in Incidence Rate
B. Increase in Awareness
C. Availability of Novel Therapeutics
D. Rise in Healthcare Expenditure
3. Epidemiology of Spinal Muscular Atrophy (SMA)…………………………………………….
A. Incidence of SMA
B. Prevalence of SMA
4. Spinal Muscular Atrophy (SMA) Therapeutics Market Segmentation………
A. By Therapy
I. Gene Replacement Therapy
II. Physical Therapy
III. Occupational Therapy
B. By Route of Administration
I. Oral
II. Intrathecal
5. Spinal Muscular Atrophy (SMA) Major Products Market Share…………………
A. Market Analysis, Insights and Forecast – By Revenue Type
6. Competitive Landscape………………………………………………………………………
A. Major Players
B. Products in Pipeline
7. Key Company Profiles………………………………………………………………………
A. Biogen Company Overview, Product & Services, Strategies & Financials
B. Roche Company Overview, Product & Services, Strategies & Financials
C. Novartis Company Overview, Product & Services, Strategies & Financials
8. Healthcare Policies and Regulatory Landscape……………………………………….
A. Policy Changes and Reimbursement Scenario
9. Factors Driving Future Growth……………………………………………………………
A. New Trends and Development of Spinal Muscular Atrophy (SMA) Therapeutics Market
B. Future Opportunities
10. Conclusion

Market Segmentation

By Therapy:

On the basis of therapy, the China spinal muscular atrophy (SMA) therapeutics market can be segmented into gene replacement therapy, physical therapy and occupational therapy.

Gene replacement therapy is the innovative therapy which is approved by US-FDA. It consists of products such as Spinraza (approved in China) and zolgensma (yet to be approved in China).

Physical therapy may help to maintain muscle strength and range of motion for as long as possible in patients with SMA. However, incorrect or too much exercise may cause more harm than good, so patients need to discuss exercise plans with a physical therapist before starting to exercise.

An occupational therapist can recommend specialized assistive equipment that may help some patients maintain their independence. These include braces for the arms and legs, orthotics (shoe inserts to improve walking ability), speech synthesizers, and wheelchairs.

By Route of Administration:

On the basis of route of administration, the China spinal muscular atrophy (SMA) therapeutics market can be segmented into oral and intrathecal. Recently approved therapies for SMA have been given through intrathecal route. For instance, in February 2019 Spinraza was approved in China and it is given by intrathecal route.

Major Players

Some of the key players in China’s spinal muscular atrophy (SMA) therapeutics market are Novartis Inc; AveXis, Inc; Biogen Inc; F. Hoffmann-La Roche AG.

Key players are adopting strategies such as mergers and acquisitions, partnerships, agreements and regulatory approvals along with an increased focus on R&D to stand out as strong competitors in the market. For instance, in February 2019 Biogen’s antisense therapy Spinraza (Nusinersen) was first approved for the treatment of Spinal Muscular Atrophy (SMA) in China.

Novartis – Zolgensma which has already received approval in the US. Novartis has its presence in China however, the drugs are not approved in China.

Research Methodology

Insights10 will provide you reports within 10 key parameters which are:

  1. Market overview
  2. Market growth drivers & restraints
  3. Epidemiology or disease type
  4. Market segmentation
  5. Market share
  6. Competitive landscape
  7. Key company profiles
  8. Healthcare policies & regulatory framework
  9. Reimbursement scenario
  10. Factors driving future growth

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The study on the market covers the analysis of the leading geographies such as North America, Europe, Asia-Pacific, and Africa for the period of 2020 to 2028. The qualitative analysis covers the industry landscape and trends, market opportunities, competitive landscape and policy and regulatory scenario and the quantitative analysis covers different market estimates and forecasts.

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