China Primary Hyperoxaluria (PH) Therapeutics Market


  • Type: Rare Disease Area
  • Published : April 2021
  • Region: Asia
  • Country: China
  • Report ID : 1612

  • Format: PPT, PDF

China Primary Hyperoxaluria (PH) Therapeutics Market: Segmented by Drug Type (Potassium Citrate, Thiazides, Magnesium, and Orthophosphates), Therapy (Cell and Gene Therapy), Distribution Channels (Clinics, Hospitals and Others)- Size, Share, Growth, Trends, and Forecasts (2020 – 2028)

SKU: 1612 Categories: ,

Report Overview

China Primary Hyperoxaluria (PH) Therapeutics market size stood at around USD xx billion in 2020 and is projected to reach USD xx billion by 2028, exhibiting a CAGR of xx% during the forecast period.

Primary hyperoxaluria (PH) is a group of rare genetic metabolic disorders that are characterized by the accumulation of a substance known as oxalate in the kidneys and other organ systems of the body. PH type I is the most common form. The global prevalence of PH type I is estimated to be 1-3 cases per 1,000,000 people. Globally PH1 accounts for 85% of patients, PH2 8-10% and PH3 5-7%. PH1 is the most severe form overall, more than 70% of PH1 patients develop end-stage kidney disease over time.

Market Drivers

China is a growing market for primary hyperoxaluria (PH) due to factors such as increase in global prevalence rate (1-3 cases per 1,000,000 people). In addition to this, other factors that contribute to the growth of market are rise in healthcare expenditure, increase in awareness and increase in R&D activities by private players.

However, there are some restraining factors for growth of primary hyperoxaluria (PH) therapeutics market in China such as undiagnosed or misdiagnosed, determining the true frequency of these conditions in the general population is difficult.

1. China Primary Hyperoxaluria (PH) Therapeutics Market Overview……………..
A. Market Size
2. Market Growth Drivers………………………………………………………………………
A. Increase in Prevalence Rate
B. Increase in Awareness
C. Increase in R&D Activities
D. Rise in Healthcare Expenditure
3. Types of Primary Hyperoxaluria (PH) …………………………………………………………
A. Primary Hyperoxaluria Type I (PH I)
B. Primary Hyperoxaluria Type II (PH II)
C. Primary Hyperoxaluria Type III (PH III)
4. Primary Hyperoxaluria (PH) Therapeutics Market Segmentation……………..
A. By Drug Type
I. Potassium Citrate
II. Thiazides
III. Magnesium
IV. Orthophosphates
B. By Therapy
I. Cell Therapy
II. Gene Therapy
C. By Distribution Channels
I. Clinics
II. Hospitals
III. Others
5. Primary Hyperoxaluria (PH) Major Products Market Share……………………
A. Market Analysis, Insights and Forecast – By Revenue Type
6. Competitive Landscape………………………………………………………………………
A. Major Players
B. Products in Pipeline
7. Key Company Profiles………………………………………………………………………
A. Alnylam Company Overview, Product & Services, Strategies & Financials
8. Healthcare Policies and Regulatory Landscape……………………………………….
A. Policy Changes and Reimbursement Scenario
9. Factors Driving Future Growth……………………………………………………………
A. New Trends and Development of Primary Hyperoxaluria (PH) Therapeutics Market
B. Future Opportunities
10. Conclusion

Market Segmentation

By Drug Type:

On the basis of drug type, the China primary hyperoxaluria (PH) therapeutics market can be segmented into Potassium Citrate, Thiazides, Magnesium, and Orthophosphates. These drugs are used along with the dietary supplementation such as Pyridoxine, also known as vitamin B6. Treatment may require the coordinated efforts of a team of specialists. Paediatricians, surgeons, specialists who assess and treat problems of the kidneys (nephrologists), specialists who assess and treat problems of the liver (hepatologists), specialists who assess and treat problems of the urinary tract (urologists).

By Therapy:

On the basis of therapy, the China primary hyperoxaluria (PH) therapeutics market can be segmented into cell therapy and gene therapy.

In gene therapy the defective gene present in a patient is either turned off and no longer able to function, as is the case with RNA interference, or is replaced with a normal gene to enable the production of the active enzyme and prevent the development and progression of the disease. These are investigational therapies.

By Distribution Channels:

On the basis of distribution channels, the China primary hyperoxaluria (PH) therapeutics market can be segmented into clinics, hospitals and others. During the forecast period (2020-2028) hospitals are the key distribution channels owing to the number of specialists required to diagnose and treat disease and easy availability of medicines in one place. In case of surgery the patients need to stay in the hospitals for 7 to 14 days. Clinics are the second largest distribution channels for the primary hyperoxaluria drug market due to which some of the patients may visit clinics for the treatment. Other distribution channels include retail and online pharmacies.

Major Players

Some of the key players in China’s primary hyperoxaluria (PH) therapeutics market are Alnylam Pharmaceuticals Inc. Dicerna Pharmaceuticals Inc.

Dicerna received a rare paediatric disease designation from the U.S. Food and Drug Administration for Nedosiran for treatment of primary hyperoxaluria. Dicerna does not has its presence in China.

Alnylam Pharmaceuticals U.S. Food and Drug Administration (FDA) approval of Oxlumo (Lumasiran), the first and only treatment approved for primary hyperoxaluria type 1 to lower urinary oxalate levels in paediatric and adult patients. The company does not have its presence in China but it has other products which are approved in China. The Lumasiran drug is yet to be approved in China.

Research Methodology

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  8. Healthcare policies & regulatory framework
  9. Reimbursement scenario
  10. Factors driving future growth

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