China ATTR (Transthyretin Amyloidosis) Therapeutics Market


  • Type: Rare Disease Area
  • Published : April 2021
  • Region: Asia
  • Country: China
  • Report ID : 1567

  • Format: PPT, PDF

China ATTR (Transthyretin Amyloidosis) Therapeutics Market – Segmented by Drug Type (Transthyretin Stabilizers, Nonsteroidal Anti-Inflammatory Drugs, Therapeutic Antisense Oligonucleotides, Monoclonal Antibodies), Distribution Channel (Hospital, Retail, Online Pharmacies), Indication (Wild and Hereditary ATTR (Transthyretin Amyloidosis)-Size, Share, Growth, Trends, And Forecasts (2019 – 2028)

SKU: 1567 Categories: ,

Report Overview

The China ATTR (Transthyretin Amyloidosis) Therapeutics market size stood at USD xx billion in 2019 and is projected to reach USD xx billion by 2028, exhibiting a CAGR of xx% during the forecast period.

The diagnosis and treatment of rare diseases are an important public health issue and a challenge for medical care in China. The prevalence rate of ATTR (Transthyretin Amyloidosis) disease in China is 1997 people per 1,00,000. With its enormous population, disparate geography and socioeconomic inequalities, China faces considerable obstacles in improving the standard of care for patients who are affected by ATTR (Transthyretin Amyloidosis) disease.

Market Drivers

China is the growing market for ATTR (Transthyretin Amyloidosis) disease due to enormous population and increasing aging population leads to increase in China’s Prevalence rate 1997 people per 1,00,000. Faster adaptation to healthcare technology, various government policies such as investing in the R&D for developing the new treatment methods, prioritized approval process by China FDA, research funding in rare diseases, tax reduction, collaboration with international communities, Reimbursement policies, and government awareness programs are leading to growth of ATTR (Transthyretin Amyloidosis) therapeutics.

There are some restraining factors for growth of ATTR (Transthyretin Amyloidosis) therapeutics market in China such as absence of official legislation, high rate of misdiagnosis and limited funding for high-cost drugs.

1. China ATTR (Transthyretin Amyloidosis) Therapeutics Market Overview..
A. Market Size
2. Market Growth Drivers……………………………………………………………………….
A. Rise in Aging Population, Increase in Prevalence
B. Growth in R&D Investments and Reimbursement Policies
C. Genetic Factors
3. Major Types of ATTR (Transthyretin Amyloidosis) ………………….…………………..
A. Wild Type ATTR (Transthyretin Amyloidosis)
B. Hereditary ATTR (Transthyretin Amyloidosis)
4. ATTR (Transthyretin Amyloidosis) Therapeutics Market Segmentation
A. By Drug Type
I. Transthyretin Stabilizers
II. Nonsteroidal Anti-Inflammatory Drugs
III. Therapeutic antisense oligonucleotides
IV. Monoclonal antibodies
B. By Indication
I. Wild Type ATTR (Transthyretin Amyloidosis)
II. Hereditary ATTR (Transthyretin Amyloidosis)
C. By Distribution Channel
I. Hospital Pharmacies
II. Retail Pharmacies
III. Online Pharmacies
5. ATTR (Transthyretin Amyloidosis) Major Products Market Share……………..
A. Market Analysis, Insights and Forecast – By Revenue Type
6. Competitive Landscape…………………………….……………………………………….
A. Major Players
B. Products in Pipeline
7. Key Company Profiles…………….………………………………………..……………….
A. Pfizer Company Product & Services, Strategies & Financials
B. Alnylam Company Product & Services, Strategies & Financials
8. Healthcare Policies and Regulatory Landscape……………………..……..……….…
A. New Policies and Reimbursement scenario
9. Factors Driving Future Growth……………………………………………………………
A. New Trends and Development of ATTR (Transthyretin Amyloidosis) Therapeutics Market
B. Future Opportunities
10. Conclusion

Market Segmentation

By Drug Type:

On the basis of the drug Type, the China ATTR (Transthyretin Amyloidosis) therapeutics market is segmented into transthyretin stabilizers, nonsteroidal anti-inflammatory drugs, therapeutic antisense oligonucleotides and monoclonal antibodies.

Transthyretin Stabilizers include drugs such as Tafamidis and Epigallocatechin-3-gallate. Nonsteroidal Anti-Inflammatory Drugs are used to control the symptoms associated with the disease and it include drug such as Diflunisal. Therapeutic antisense oligonucleotides consist of Inotersen. Monoclonal antibodies are also used for the treatment it includes Dezamizumab.

By Distribution Channel:

Based on the distribution channel, the China ATTR (Transthyretin Amyloidosis) therapeutics market has been segmented into hospitals, retail, online pharmacies. During the forecast period (2019-2028) hospital pharmacies is the key distribution channel segment of the ATTR (Transthyretin Amyloidosis) therapeutics market. Clinical examination and supporting laboratory investigations for the diagnosis of ATTR (Transthyretin Amyloidosis) are best possible in hospitals. Retail and online pharmacies are the second largest distribution channels.

By Indication:

On the basis of the indication, the China ATTR (Transthyretin Amyloidosis) therapeutics market is segmented into wild type ATTR amyloidosis and hereditary ATTR amyloidosis.

Wild Type ATTR Amyloidosis: Wild type does not involve abnormal DNA and cannot be passed onto family members. Instead, as you get older, the normal TTR protein becomes unstable, misfolds and forms amyloid fibrils.

Hereditary ATTR Amyloidosis: In this form, there is a change in the DNA that is inherited and can be passed from one generation to the next. This makes the TTR protein more unstable and more likely to form amyloid fibrils. In this type genetic mutation prevents TTR protein, which is made in the liver, from having its normal structure. Instead TTR misfolds and accumulates as amyloid deposits in the body (heart, nerves, GI tract) causing debilitating symptoms.


Major Players

Some of the key players in the ATTR (Transthyretin amyloidosis) therapeutics market are Pfizer Inc.; Ionis Pharmaceuticals inc.; Alnylam Pharmaceuticals Inc.;

Key players are adopting various strategies such as strategic collaboration to increase their market share and also to develop new therapy for effective treatment of the disease. For instance, Alnylam and Genzyme (a Sanofi company) form alliance to develop and commercialize RNAi therapeutics targeting transthyretin (TTR) for the treatment of transthyretin mediated amyloidosis in Asia-Pacific countries (China).

Product pipeline of Alnylam Pharmaceuticals Inc. – Vutrisiran (in Phase 2-Phase 3 development).

Research Methodology

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  1. Market overview
  2. Market growth drivers & restraints
  3. Epidemiology or disease type
  4. Market segmentation
  5. Market share
  6. Competitive landscape
  7. Key company profiles
  8. Healthcare policies & regulatory framework
  9. Reimbursement scenario
  10. Factors driving future growth

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