China ATTR (Transthyretin Amyloidosis) Therapeutics Market

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  • Type: Rare Disease Area
  • Published : April 2021
  • Region: Asia
  • Country: China
  • Report ID : 1567

  • Format: PPT, PDF

China ATTR (Transthyretin Amyloidosis) Therapeutics Market – Segmented by Drug Type (Transthyretin Stabilizers, Nonsteroidal Anti-Inflammatory Drugs, Therapeutic Antisense Oligonucleotides, Monoclonal Antibodies), Distribution Channel (Hospital, Retail, Online Pharmacies), Indication (Wild and Hereditary ATTR (Transthyretin Amyloidosis)-Size, Share, Growth, Trends, And Forecasts (2019 – 2028)

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Report Overview

The China ATTR (Transthyretin Amyloidosis) Therapeutics market size stood at USD xx billion in 2019 and is projected to reach USD xx billion by 2028, exhibiting a CAGR of xx% during the forecast period.

The diagnosis and treatment of rare diseases are an important public health issue and a challenge for medical care in China. The prevalence rate of ATTR (Transthyretin Amyloidosis) disease in China is 1997 people per 1,00,000. With its enormous population, disparate geography and socioeconomic inequalities, China faces considerable obstacles in improving the standard of care for patients who are affected by ATTR (Transthyretin Amyloidosis) disease.

Market Drivers

China is the growing market for ATTR (Transthyretin Amyloidosis) disease due to enormous population and increasing aging population leads to increase in China’s Prevalence rate 1997 people per 1,00,000. Faster adaptation to healthcare technology, various government policies such as investing in the R&D for developing the new treatment methods, prioritized approval process by China FDA, research funding in rare diseases, tax reduction, collaboration with international communities, Reimbursement policies, and government awareness programs are leading to growth of ATTR (Transthyretin Amyloidosis) therapeutics.

There are some restraining factors for growth of ATTR (Transthyretin Amyloidosis) therapeutics market in China such as absence of official legislation, high rate of misdiagnosis and limited funding for high-cost drugs.

1. China ATTR (Transthyretin Amyloidosis) Therapeutics Market Overview..
A. Market Size
2. Market Growth Drivers……………………………………………………………………….
A. Rise in Aging Population, Increase in Prevalence
B. Growth in R&D Investments and Reimbursement Policies
C. Genetic Factors
3. Major Types of ATTR (Transthyretin Amyloidosis) ………………….…………………..
A. Wild Type ATTR (Transthyretin Amyloidosis)
B. Hereditary ATTR (Transthyretin Amyloidosis)
4. ATTR (Transthyretin Amyloidosis) Therapeutics Market Segmentation
A. By Drug Type
I. Transthyretin Stabilizers
II. Nonsteroidal Anti-Inflammatory Drugs
III. Therapeutic antisense oligonucleotides
IV. Monoclonal antibodies
B. By Indication
I. Wild Type ATTR (Transthyretin Amyloidosis)
II. Hereditary ATTR (Transthyretin Amyloidosis)
C. By Distribution Channel
I. Hospital Pharmacies
II. Retail Pharmacies
III. Online Pharmacies
5. ATTR (Transthyretin Amyloidosis) Major Products Market Share……………..
A. Market Analysis, Insights and Forecast – By Revenue Type
6. Competitive Landscape…………………………….……………………………………….
A. Major Players
B. Products in Pipeline
7. Key Company Profiles…………….………………………………………..……………….
A. Pfizer Company Product & Services, Strategies & Financials
B. Alnylam Company Product & Services, Strategies & Financials
8. Healthcare Policies and Regulatory Landscape……………………..……..……….…
A. New Policies and Reimbursement scenario
9. Factors Driving Future Growth……………………………………………………………
A. New Trends and Development of ATTR (Transthyretin Amyloidosis) Therapeutics Market
B. Future Opportunities
10. Conclusion

Market Segmentation

By Drug Type:

On the basis of the drug Type, the China ATTR (Transthyretin Amyloidosis) therapeutics market is segmented into transthyretin stabilizers, nonsteroidal anti-inflammatory drugs, therapeutic antisense oligonucleotides and monoclonal antibodies.

Transthyretin Stabilizers include drugs such as Tafamidis and Epigallocatechin-3-gallate. Nonsteroidal Anti-Inflammatory Drugs are used to control the symptoms associated with the disease and it include drug such as Diflunisal. Therapeutic antisense oligonucleotides consist of Inotersen. Monoclonal antibodies are also used for the treatment it includes Dezamizumab.

By Distribution Channel:

Based on the distribution channel, the China ATTR (Transthyretin Amyloidosis) therapeutics market has been segmented into hospitals, retail, online pharmacies. During the forecast period (2019-2028) hospital pharmacies is the key distribution channel segment of the ATTR (Transthyretin Amyloidosis) therapeutics market. Clinical examination and supporting laboratory investigations for the diagnosis of ATTR (Transthyretin Amyloidosis) are best possible in hospitals. Retail and online pharmacies are the second largest distribution channels.

By Indication:

On the basis of the indication, the China ATTR (Transthyretin Amyloidosis) therapeutics market is segmented into wild type ATTR amyloidosis and hereditary ATTR amyloidosis.

Wild Type ATTR Amyloidosis: Wild type does not involve abnormal DNA and cannot be passed onto family members. Instead, as you get older, the normal TTR protein becomes unstable, misfolds and forms amyloid fibrils.

Hereditary ATTR Amyloidosis: In this form, there is a change in the DNA that is inherited and can be passed from one generation to the next. This makes the TTR protein more unstable and more likely to form amyloid fibrils. In this type genetic mutation prevents TTR protein, which is made in the liver, from having its normal structure. Instead TTR misfolds and accumulates as amyloid deposits in the body (heart, nerves, GI tract) causing debilitating symptoms.

 

Major Players

Some of the key players in the ATTR (Transthyretin amyloidosis) therapeutics market are Pfizer Inc.; Ionis Pharmaceuticals inc.; Alnylam Pharmaceuticals Inc.;

Key players are adopting various strategies such as strategic collaboration to increase their market share and also to develop new therapy for effective treatment of the disease. For instance, Alnylam and Genzyme (a Sanofi company) form alliance to develop and commercialize RNAi therapeutics targeting transthyretin (TTR) for the treatment of transthyretin mediated amyloidosis in Asia-Pacific countries (China).

Product pipeline of Alnylam Pharmaceuticals Inc. – Vutrisiran (in Phase 2-Phase 3 development).

Research Methodology

Insights10 will provide you reports within 10 key parameters which are:

  1. Market overview
  2. Market growth drivers & restraints
  3. Epidemiology or disease type
  4. Market segmentation
  5. Market share
  6. Competitive landscape
  7. Key company profiles
  8. Healthcare policies & regulatory framework
  9. Reimbursement scenario
  10. Factors driving future growth

Based on our many years of experience, we believe that these are the parameters that are critical to decision making for business stakeholders. Our focused approach to develop reports focused on 10 key parameters, enabled us to arrive at the name “Insights10”.

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The top-down approach mainly used for new product forecasting and bottom-up approach is used for demand estimation of any product for different countries summed up to form total market. We are able to round off insights and build stronger forecasts because we always do both these methods and triangulate the final numbers.

The study on the market covers the analysis of the leading geographies such as North America, Europe, Asia-Pacific, and Africa for the period of 2020 to 2028. The qualitative analysis covers the industry landscape and trends, market opportunities, competitive landscape and policy and regulatory scenario and the quantitative analysis covers different market estimates and forecasts.

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We make sure to finalize the numbers in alignment to the market research. Firstly, our internal experts ensure thorough validation and checking to ensure the accurate and precise analysis and then validation is also done using multiple data analysis model.  Two level validation is done and entails finalization of report scope and to way of representation pattern.

Stage III: Interpretation and Presentation

Analysis & Interpretation: The information gathered is then analysed and synthesized. A second series of interviews are done if necessary to check and validate. The future opportunities are analysed by understanding product commercialization and many other factors. It also comprises the analysis of data discrepancies observed across various data sources. Information procured from secondary and primary results are then, interpreted by considering following parameters: (a partial list)

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  • Market Segment based analysis to obtain revenue / volume
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The foreign exchange rates are calculated on the respective dates and for the respective regions covered in the study.

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