China Adrenoleukodystrophy (ALD) Therapeutics Market

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  • Type: Rare Disease Area
  • Published : April 2021
  • Region: Asia
  • Country: China
  • Report ID : 1593

  • Format: PPT, PDF

China Adrenoleukodystrophy (ALD) Therapeutics Market: Segmented by Therapy (Gene Therapy, Steroid Therapy and Physical Therapy), Route of Administration (Intravenous and Subcutaneous), Distribution Channel (Hospital, Retail and Online Pharmacies)- Size, Share, Growth, Trends, and Forecasts (2020 – 2028)

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Report Overview

China Adrenoleukodystrophy (ALD) Therapeutics market size stood at around USD xx billion in 2020 and is projected to reach USD xx billion by 2028, exhibiting a CAGR of xx% during the forecast period.

Adrenoleukodystrophy (ALD) is a rare, genetic, X-linked metabolic disorder caused by mutations in the ABCD1 gene that result in a deficiency in a peroxisomal protein called adrenoleukodystrophy protein (ALDP). Globally AMN and cALD are the two most common phenotypes of X-ALD, which account for 45% and 35% respectively. The global incidence of X-ALD is approximately 6.2/100,000 live births. X-ALD is included in the first China Rare Disease Catalogue published in 2018.The age of onset of cALD patients is typically 4-8 years old.

Market Drivers

China is a growing market for adrenoleukodystrophy (ALD) due to increase in global incidence rate (6.2/100,000 live births). In addition to this, other factors that contribute to the growth of the market are inevitable inheritance of the disease and increase in R&D activities by pharmaceutical companies.

However, there are some restraining factors for growth of adrenoleukodystrophy (ALD) drugs market in China such as overall high cost of treatment and unfavourable reimbursement.

1. China Adrenoleukodystrophy (ALD) Therapeutics Market Overview………….
A. Market Size
2. Market Growth Drivers………………………………………………………………………
A. Inevitable Inheritance of the Disease
B. Increase in Prevalence Rate and Incidence Rate
C. Increase in R&D Activities
3. Types of Adrenoleukodystrophy (ALD)………………………………………………………
A. Adrenomyeloneuropathy (AMN)
B. Adult Cerebral ALD
C. Childhood Cerebral ALD
D. Addison’s-Only ALD
4. Adrenoleukodystrophy (ALD) Therapeutics Market Segmentation…………
A. By Therapy
I. Gene Therapy
II. Steroid Therapy
III. Physical Therapy
B. By Route of Administration
I. Subcutaneous Route
II. Intravenous Route
C. By Distribution Channels
I. Hospital Pharmacies
II. Retail Pharmacies
III. Online Pharmacies
5. Adrenoleukodystrophy (ALD) Major Products Market Share……………………
A. Market Analysis, Insights and Forecast – By Revenue Type
6. Competitive Landscape………………………………………………………………………
A. Major Players
B. Products in Pipeline
7. Key Company Profiles………………………………………………………………………
A. Sperogenix Company Overview, Product & Services, Strategies & Financials
B. Minoryx Company Overview, Product & Services, Strategies & Financials
8. Healthcare Policies and Regulatory Landscape……………………………………….
A. Policy Changes and Reimbursement Scenario
9. Factors Driving Future Growth……………………………………………………………
A. New Trends and Development of Adrenoleukodystrophy (ALD) Therapeutics Market
B. Future Opportunities
10. Conclusion

Market Segmentation

By Therapy:

On the basis of therapy, the China’s adrenoleukodystrophy (ALD) therapeutics market can be segmented into gene therapy, steroid therapy and physical therapy.

Gene therapy is the most promising treatment method, but it needs to be further explored due to technical issues.

Steroid therapy, corticosteroid replacement therapy is often necessary, but this treatment is not effective for neurological damage, cannot improve symptoms, and cannot prevent the deterioration of the disease.

Physical therapy is helpful for men with the adrenomyeloneuropathy (AMN) form of the disease.

By Route of Administration:

On the basis of route of administration, China’s adrenoleukodystrophy (ALD) therapeutics market can be segmented into intravenous and subcutaneous routes. The Intravenous route is mainly used in China. The general principle of this route in treatment of adrenoleukodystrophy is that early use is better than late use; larger doses are better than smaller doses.

By Distribution Channel:

On the basis of distribution channel, China’s adrenoleukodystrophy (ALD) therapeutics market can be segmented into retail, online and hospital pharmacies. During the forecast period (2020-2028) hospital pharmacies are the key distribution channels as they have a large patient base compared to other healthcare facilities and they also conduct various clinical trials. Retail pharmacy is less dominating as compared to hospital pharmacy due to a smaller number of approved drugs and sometimes non availability of medicines.

Major Players

Some of the key players in China’s adrenoleukodystrophy (ALD) therapeutics market are Sperogenix Therapeutics; Minoryx Therapeutics; Lonza Houston, Inc; Shufang Pharmaceutical.

Key players are adapting various strategies such as distribution partnership, collaboration and licensing agreement to increase the product awareness and market share of the product. For instance, Minoryx Therapeutics and Sperogenix Therapeutics enter into an exclusive license agreement to develop and commercialize Leriglitazone in mainland China, Hong Kong and Macau. Under this agreement Sperogenix will receive exclusive rights to develop and commercialize Leriglitazone in mainland China, Hong Kong special administrative region (SAR) and Macau SAR for the treatment of X-linked adrenoleukodystrophy (X-ALD), a life-threatening orphan neurological condition.

In June 2016, Bluebird Bio entered into a strategic manufacturing agreement with Lonza Houston, Inc., providing for the future commercial production of our drug products Lenti-D in cerebral adrenoleukodystrophy.

Bluebird Bio does not have its direct presence in China, but it is collaborated with Lonza Houston group (has its presence in China).

Sperogenix Shufang’s introduction of X-chain adrenoleukodystrophy experimental drugs based on the actual clinical needs of doctors and patients.

Research Methodology

Insights10 will provide you reports within 10 key parameters which are:

  1. Market overview
  2. Market growth drivers & restraints
  3. Epidemiology or disease type
  4. Market segmentation
  5. Market share
  6. Competitive landscape
  7. Key company profiles
  8. Healthcare policies & regulatory framework
  9. Reimbursement scenario
  10. Factors driving future growth

Based on our many years of experience, we believe that these are the parameters that are critical to decision making for business stakeholders. Our focused approach to develop reports focused on 10 key parameters, enabled us to arrive at the name “Insights10”.

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The study on the market covers the analysis of the leading geographies such as North America, Europe, Asia-Pacific, and Africa for the period of 2020 to 2028. The qualitative analysis covers the industry landscape and trends, market opportunities, competitive landscape and policy and regulatory scenario and the quantitative analysis covers different market estimates and forecasts.

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We make sure to finalize the numbers in alignment to the market research. Firstly, our internal experts ensure thorough validation and checking to ensure the accurate and precise analysis and then validation is also done using multiple data analysis model.  Two level validation is done and entails finalization of report scope and to way of representation pattern.

Stage III: Interpretation and Presentation

Analysis & Interpretation: The information gathered is then analysed and synthesized. A second series of interviews are done if necessary to check and validate. The future opportunities are analysed by understanding product commercialization and many other factors. It also comprises the analysis of data discrepancies observed across various data sources. Information procured from secondary and primary results are then, interpreted by considering following parameters: (a partial list)

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The foreign exchange rates are calculated on the respective dates and for the respective regions covered in the study.

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