Ankylosing Spondylitis Market Worldwide


  • Type: Common Disease Area
  • Published : March 2021
  • Region: Worldwide
  • Country: Other
  • Report ID : 136

  • Format: PPT, PDF

Global Ankylosing Spondylitis Market: Size, Share & Trends Analysis Report by Drug (Cosentyx, Humira, Simponi, Remicade, Enbrel, Cimzia), by Region (North America, APAC, Europe, MEA), and Segment Forecasts, 2019 – 2028


Report Overview

The global ankylosing spondylitis market size stood at around USD 4.8 billion in 2022 and is projected to reach USD 8.45 billion by 2028, exhibiting a CAGR of 8.21% during the forecast period.

The introduction of novel products as well as the entry of biosimilars is expected to drive the market growth over the forecast period. The increasing prevalence of the disease is further anticipated to drive the market. According to a study published in Oxford University Press, the number of cases in Europe were 1.30 to 1.56 million and 4.63 to 4.98 million in the Asia Pacific. Commercialization of novel products and increasing collaborations between companies is expected to accelerate the market growth.

Market Drivers

The increasing prevalence of ankylosing spondylitis itself is a major factor impelling the global ankylosing spondylitis treatment market. In addition, factors such as rising awareness, technological advancements, government initiatives and improvement in the reimbursement scenario augur well for the global ankylosing spondylitis treatment market. However, factors such as high treatment costs and a dearth of experienced professionals are restraining the global ankylosing spondylitis treatment market. In addition, a low adoption rate of ankylosing spondylitis treatment options is restraining the market.
Growing population and economies in the developing countries such as India and China are expected to offer lucrative opportunities for the global ankylosing spondylitis treatment market. Innovation of new, more efficient products is expected to offer growth opportunities for the global ankylosing spondylitis treatment market. A rising number of mergers and acquisitions, new product launches, and more collaborations and partnerships are some of the latest trends that have been observed in the global ankylosing spondylitis treatment market.



  1. Global Adrenoleukodystrophy (ALD) Market Overview……………………………
    1. Market Size
  2. Market Growth Drivers……………………………………………………..……………….
    1. Increasing Penetration of Key Players in the AS Market
    2. Presence of Strong Product Pipeline
    3. Favorable Reimbursement Policies
  3. Five Forces Analysis………………………………………………………………………….
    1. Supplier Power
    2. Buyer Power
    3. Substitution Threat
    4. New entrants’ Threat
    5. Competitive Rivalry
  4. Ankylosing Spondylitis Market Segmentation……………..…………………………..
    1. By Drug
      1. Cosentyx
      2. Humira
      3. Simponi
      4. Remicade
      5. Enbrel
      6. Cimzia
    2. By Geography
      1. North America Market Analysis
      2. Europe Market Analysis
      3. Asia-Pacific Market Analysis
      4. Latin America, Middle-East and Africa Market Analysis
  5. Ankylosing Spondylitis Major Drugs Market Share……………………………………
    1. Key Findings
    2. Market Analysis, Insights and Forecast to 2028
  6. Competitive Landscape………………………………………………………….………..
    1. Major Players
    2. Products in Pipeline
  7. Key Company Profiles………………………………………………………………………
    1. AbbVie, Inc. Company overview, Product & Services, Strategies & Financials
    2. Amgen, Inc. Company overview, Product & Services, Strategies & Financials
    3. Pfizer, Inc. Company profile, Product & Services, Strategies & Financials
  8. Potential Growth Opportunities………………………………………………..…………
    1. Advancements in drug development
    2. Untapped markets in developing economies
  9. Factors Driving Future Growth…………………………………………………………..
    1. Key Industry Trends and Recent Developments in Ankylosing Spondylitis Market
    2. Future Opportunities
  10. Conclusion

Market Segmentation

By Drug Class:

Humira led the ankylosing spondylitis market in 2019 and accounted for over 25% of the overall share owing to its low cost and high efficacy. However, the product is expected to have declining sales over the forecast period due to patent expiry in Europe along with direct biosimilar competition in certain markets.

On the other hand, Cosentyx is expected to be the fastest-growing segment over the forecast period. In October 2019, Novartis received the European Commission approval for Cosentyx for non-radiographic axial spondyloarthritis. The company further plans to submit the label update application to the U.S. FDA and once it is approved, the product is projected to have significant growth over the forecast period.

However, the patent expiry of blockbuster products restrains the market growth. In October 2018, the patent of AbbVie’s proprietary product Humira expired in the EU. Furthermore, the EU patent of Enbrel (Amgen Inc./Pfizer Inc.) and Remicade (Johnson & Johnson Services, Inc./Merck & Co., Inc.) expired in 2015.

By Region:

North America was the largest region in 2019 and accounted for over 60% of the total share owing to high disease prevalence in U.S. and Canada and commercial sales of branded drugs. The patent expiry of branded drugs has provided an opportunity for biosimilar. For instance, the patent expiry of Remicade in 2015 resulted in the introduction of Inflectra in 2016, Ixifi & Renflexis in 2017, and Avsola in 2019.

In addition, initiatives undertaken by major players support market growth in North America. In January 2019, Novartis AG and TrialSpark collaborated with an aim to increase patient access to clinical trials. This collaboration will shorten the enrolment timeline and help in the faster development of new therapies.

Recently, the trials were launched in various sites in New York to test a treatment for ankylosing spondylitis. The Asia Pacific is projected to be the fastest-growing region owing to increasing disease incidence in developing countries like China, India, and Indonesia. Furthermore, favorable reimbursement policies in China is supporting regional market growth.

Key Industry Players

Continuous R&D efforts by various pharmaceutical companies to develop better treatment options are expected to boost market growth over the forecast period. For instance, Pfizer Inc. is currently recruiting patients for determining the remission criterion at a 6-month time interval for etanercept. Key companies are also adopting different strategies, such as label expansion and M&A, to increase their market share. For instance, in May 2019, AbbVie Inc. announced the patent extension of its blockbuster drug, Humira, till 2023 in U.S. after the settlement with Boehringer Ingelheim International GmbH. This deal with Boehringer enabled the company to maintain a monopoly in U.S. Some of the prominent players in the ankylosing spondylitis market include: AbbVie, Inc., Amgen, Inc., Pfizer, Inc., Novartis AG, Eli Lilly and Company, UCB, Inc., Johnson & Johnson Services, Inc., Merck & Co., Inc.

Research Methodology

Insights10 will provide you reports within 10 key parameters which are:

  1. Market overview
  2. Market growth drivers & restraints
  3. Epidemiology or disease type
  4. Market segmentation
  5. Market share
  6. Competitive landscape
  7. Key company profiles
  8. Healthcare policies & regulatory framework
  9. Reimbursement scenario
  10. Factors driving future growth

Based on our many years of experience, we believe that these are the parameters that are critical to decision making for business stakeholders. Our focused approach to develop reports focused on 10 key parameters, enabled us to arrive at the name “Insights10”.

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Stage I: Market Data Collection

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Data Sources: We have access to multiple highly reliable free and subscription data sources. We have many years of experience to understand which sources are more dependable for what and which to prefer for the reliable and latest information. The key sources of information include the following, but are not limited to:

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Market Trends: We generally look at macro parameter and micro indicators. The macro parameters includes changes in government policies, demand and supply of the market, government intervention programs and major market share. The micro indicators GDP growth, market size, market volume etc. We also understand nuances specific to each country like US, Canada, India, Germany, etc. and have worked across 60+ countries and hence no only understand global trends, but how these differ by country, how payment models, market structure, cultural parameters, etc. differ in each country.

Market Sizing and Analysis: Our expert data analytics team has created various market forecast models by employing the top-down approach i.e. start with large overall market and segment different areas and bottom-up approach i.e. start with population and epidemiology and roll up based on spend, etc., estimating the size of the market, and distributing among the geographic and/or product segments.

The top-down approach mainly used for new product forecasting and bottom-up approach is used for demand estimation of any product for different countries summed up to form total market. We are able to round off insights and build stronger forecasts because we always do both these methods and triangulate the final numbers.

The study on the market covers the analysis of the leading geographies such as North America, Europe, Asia-Pacific, and Africa for the period of 2020 to 2028. The qualitative analysis covers the industry landscape and trends, market opportunities, competitive landscape and policy and regulatory scenario and the quantitative analysis covers different market estimates and forecasts.

Data Triangulation & Validation:

Data triangulation of various sources and results of the research are carried out by benchmarking with reliable sources such as industry statistics, statistical databases and the company level averages etc.

We make sure to finalize the numbers in alignment to the market research. Firstly, our internal experts ensure thorough validation and checking to ensure the accurate and precise analysis and then validation is also done using multiple data analysis model.  Two level validation is done and entails finalization of report scope and to way of representation pattern.

Stage III: Interpretation and Presentation

Analysis & Interpretation: The information gathered is then analysed and synthesized. A second series of interviews are done if necessary to check and validate. The future opportunities are analysed by understanding product commercialization and many other factors. It also comprises the analysis of data discrepancies observed across various data sources. Information procured from secondary and primary results are then, interpreted by considering following parameters: (a partial list)

  • Establishing market drivers and trends
  • Analyzing regulatory landscape to understand future growth
  • Market Segment based analysis to obtain revenue / volume
  • Analyzing current needs and determining penetration to estimate market

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Data curated from the analysis and interpretation are drawn to portray all in one consolidated report.

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The foreign exchange rates are calculated on the respective dates and for the respective regions covered in the study.

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